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Β-Hydroxy β-methylbutyryl-CoA

Β-Hydroxy β-methylbutyryl-CoA

β-Hydroxy β-methylbutyryl-coenzyme A (HMB-CoA), also known as 3-hydroxyisovaleryl-CoA, is a metabolite of L-leucine that is produced in the human body. Its immediate precursors are β-hydroxy β-methylbutyric acid (HMB) and β-methylcrotonoyl-CoA (MC-CoA). It can be metabolized into HMB, MC-CoA, and HMG-CoA in humans.

Metabolic pathway

Notes

References

Tags

  • Biochemistry stubs
  • Biomolecules
  • Metabolism
  • Thioesters of coenzyme A