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13-Hydroxylergotrile

13-Hydroxylergotrile

13-Hydroxylergotrile, also known as 2-chloro-6-methyl-13-hydroxyergoline-8β-acetonitrile, is a dopamine receptor agonist of the ergoline family. It is an active metabolite of the never-marketed antiparkinsonian agent lergotrile (LY-79907). The drug has been found to be 100-fold more potent as a dopamine receptor agonist than lergotrile itself in vitro. 13-Hydroxylergotrile was first described in the scientific literature by 1978.

See also Substituted ergoline 13-Hydroxy-LSD

References

Tags

  • Chloroarenes
  • Dopamine agonists
  • Drugs not assigned an ATC code
  • Ergolines
  • Human drug metabolites
  • Hydroxyarenes
  • Nervous system drug stubs
  • Nitriles
  • Prolactin inhibitors