A1APU (10105-368-30-605-0) is a negative allosteric modulator (NAM) of the μ-opioid receptor (MOR) which has been developed as a potential treatment for opioid overdose. In animal studies it increases the potency and effective duration of naloxone making it able to block opioid-induced respiratory depression at a tenth of the normal dose.
See also MS1 (drug)
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