Actin-binding proteins (also known as ABPs) are proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both. Many actin-binding proteins, including α-actinin, β-spectrin, dystrophin, utrophin and fimbrin, do this through the actin-binding calponin homology domain. This is a list of actin-binding proteins in alphabetical order.
0–9 25kDa 25kDa ABP from aorta 30akDA 30bkDa 34kDA 45kDa 110 kD dimer ABP 110 kD (Drebrin) p53 p58gag p185neu p116rip
A a-actinin Abl ABLIM Actin-Interacting MAPKKK Ssk2p ABP120 ABP140 Abp1p ABP280 (Filamin) ABP50 (EF-1a) Acan 125 (Carmil) ActA Actibind Actin Actinfilin Actinogelin Actin-regulating kinases Actin-Related Proteins Actobindin Actolinkin Actopaxin Actophorin Acumentin (= L-plastin) Adducin ADF/Cofilin Adseverin (scinderin) Afadin AFAP-110 Affixin Aginactin AIP1 Aldolase Angiogenin Anillin Annexins Aplyronine Archvillin (isoform of Supervillin) Arginine kinase Arp2/3 complex
B Band 4.1 Band 4.9 (Dematin) b-actinin b-Cap73 Bifocal Bistramide A BPAG1 Brevin (Gelsolin)
C c-Abl Calpactin (Annexin) CHO1 Cortactin CamKinase II Calponin Chondramide Cortexillin CAP Caltropin CH-ILKBP CPb3 Cap100 Calvasculin Ciboulot Coactosin CAP23 CARMIL Acan125 Cingulin Cytovillin (Ezrin) CapZ/Capping Protein a-Catenin Cofilin CR16 Caldesmon CCT Comitin Calicin Centuarin Coronin
D DBP40 Drebrin Dematin (Band 4.9) Dynacortin Destrin (ADF/cofilin) Dystonins Diaphanous Dystroglycan DNase I Dystrophin Doliculide Dolastatins
E EAST Endossin EF-1a (ABP50) Eps15 EF-1b EPLIN EF-2 Epsin EGF receptor ERK ENC-1 ERM proteins (ezrin, radixin, moesin, plus merlin) END3p Ezrin (the E of ERM protein family)
F F17R Fodrin (spectrin) Fascin Formins Fessilin Frabin FHL3 Fragmin Fhos Filamin-A Fimbrin (plastin)
G GAP43 Glycogenins Gas2 G-proteins Gastrin-Binding Protein Gelactins I-IV Gelsolins Girdin Glucokinase
H Harmonin b Hrp36 Hexokinase Hrp65-2 Hectochlorin HS1 (actin binding protein) Helicase II Hsp27 HIP1 (Huntingtin Interacting protein 1) Hsp70 Histactophilin Hsp90 Histidine rich protein II Hsp100
I Inhibitor of apoptosis (IAP) Insertin Interaptin IP3Kinase A (Inositol 1,4,5-trisphosphate 3-kinase A) IQGAP Integrins
J Jaspisamide A Jasplakinolide
K Kabiramide C Kaptin Kettin Kelch protein
L 5-Lipoxygenase Limatin Lim Kinases Lim Proteins L-plastin Lymphocyte Specific Protein 1 (LSP1)
M MACF1 MacMARKS Mena Myopodin MAP1A Merlin (related to the ERM proteins) Myosins MAP-1C Metavinculin Moesin (the M of ERM proteins) Myosin light chain kinase MAL Mip-90 Myosin Light Chain A1 MARKS MIM MAYP Mycalolide (a macroglide drug) Mayven Myelin basic protein
N Naphthylphthalamic acid binding protein (NPA) N-RAP Nebulin N-WASP Neurabin Nullo Neurexins Neurocalcin Nexillin
O OYE2
P Palladin Plastin p30 PAK (p21-activated Kinase) Plectin p47PHOX Parvin (actopaxin) Prefoldin p53 PASK (Proline, Alanine rich Ste20 related Kinase) Presenilin I p58 Phalloidin (not a protein; a small cyclic peptide) Profilin p185neu Ponticulin Protein kinase C Porin P.IB Prk1p (actin regulating kinase)
R Radixin (the R of ERM proteins) Rapsyn Rhizopodin RPL45 RTX toxin (Vibrio cholerae) RVS 167
S Sac6 Sla1p Srv2 (CAP) S-adenosyl-L-homocysteine hydrolase, (SAHH) Sla2p Synaptopodin Scinderin (adseverin) Synapsins Scruin Spectrin Severin Spectraplakins SVSII Shot (Short stop) Spire Shroom Smitin (Smooth Musc.Titin) Supervillin SipA Smoothelin Sucrose synthetase SipC Sra-1 Spinophilin Ssk2p Swinholide
T Talin protein Toxophilin Twinfilin Tau Trabeculin Twinstar TCP-1 Transgelin Transgelin 2 Transgelin 3 Tensin Tropomodulin Thymosin Tropomyosin Titin Troponin TOR2 Tubulin bIV
U Ulapualide Utrophin Unc-87 Unc-60 (ADF/cofilins)
V VASP Vav Verprolin VDAC Vibrio cholerae RTX toxin Villin Vinculin Vitamin D-binding protein
W WIP WASp
Y Y-box proteins YpkA (YopO)
Z Zipper protein Zo-1 Zyxin
See also
References
External links The Encyclopaedia of Actin-Binding Proteins (and Drugs)– alphabetical list, sourced profile for each Maciver, Sutherland (ed.). "The Encyclopaedia of Actin-Binding Proteins (and Drugs)". Maciver Lab Web Page (online ed.). School of Biomedical Sciences, University of Edinburgh. Archived from the original on 2005-11-24. Actin-Binding+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)