The Bradsher cycloaddition reaction, also known as the Bradsher cyclization reaction, is a form of the Diels–Alder reaction which involves the [4+2] addition of a common dienophile with a cationic aromatic azadiene such as acridizinium or isoquinolinium. The Bradsher cycloaddition was first reported by C. K. Bradsher and T. W. G. Solomons in 1958.
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