CHF-1024, also known as 5,6-dihydroxy-2-methylaminotetralin, is a dopamine D2 receptor agonist and α2-adrenergic receptor agonist of the 2-aminotetralin family. It is a cyclized phenethylamine analogue of the neurotransmitter dopamine. The drug is the active form of nolomirole (CHF-1035), a prodrug of CHF-1024 and the N,N-diisobutyryl diester of the compound. Nolomirole was investigated for the treatment of heart failure but was never marketed.
See also Chiesi Farmaceutici Nolomirole Cyclized phenethylamine Rotigotine 5-OH-DPAT 7-OH-DPAT Carmoxirole
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