Chloroacetamide (2-chloroacetamide) is a chlorinated organic compound with the molecular formula ClCH2CONH2. It is a colorless solid although older samples appear yellow. It has a characteristic odor and is readily soluble in water. It has the structure Cl−CH2−C(=O)−NH2.
Production Chloroacetamide is produced by ammonolysis of esters of chloroacetic acid:
ClCH2CO2CH3 + NH3 → ClCH2C(O)NH2 + CH3OH
Uses Chloroacetamide has been used as an herbicide, preservative. and in the manufacturing of pharmaceuticals.
Hazards Chloroacetamide is toxic, irritates eyes and skin, and may cause an allergic reaction. It is suspected of reproductive toxicity and teratogenicity.
See also Novosphingobium chloroacetimidivorans, a bacterium named after its ability to degrade chloroacetamide
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