Chromosome 11 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome. Chromosome 11 spans about 135 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells. The shorter arm (p arm) is termed 11p while the longer arm (q arm) is 11q. At about 21.5 genes per megabase, chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome. More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene and multi-gene clusters along the chromosome.
Gene
Number of genes The following are some of the gene count estimates of human chromosome 11. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.
Gene list
The following is a partial list of genes on human chromosome 11. For complete list, see the links in the infobox on the right.
Diseases and disorders The following diseases and disorders are some of those related to genes on chromosome 11:
Cytogenetic band
References
External links
National Institutes of Health. "Chromosome 11". Genetics Home Reference. Archived from the original on August 3, 2004. Retrieved 2017-05-06. "Chromosome 11". Human Genome Project Information Archive 1990–2003. Retrieved 2017-05-06.