Chromosome 18 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 18 spans about 80 million base pairs (the building material of DNA) and represents about 2.5 percent of the total DNA in cells.
Genes
Number of genes The following are some of the gene count estimates of human chromosome 18. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.
Gene list
The following is a partial list of genes on human chromosome 18. For complete list, see the link in the infobox on the right.
Diseases and disorders The following diseases are some of those related to genes on chromosome 18:
Erythropoietic protoporphyria Hereditary hemorrhagic telangiectasia Niemann–Pick disease type C Porphyria Selective mutism Edwards syndrome (trisomy 18) Tetrasomy 18p Monosomy 18p Pitt–Hopkins syndrome 18q21 Distal 18q- (distal deletion) Proximal 18q- (proximal deletion)
Cytogenetic band
References
External links
Chromosome18.org Chromosome18 Registry And Research Society in Europe. National Institutes of Health. "Chromosome 18". Genetics Home Reference. Archived from the original on August 3, 2004. Retrieved 2017-05-06. "Chromosome 18". Human Genome Project Information Archive 1990–2003. Retrieved 2017-05-06.