Copper naproxen is a chemical complex of Cu2+ chelated with the anti-inflammatory drug naproxen. Copper complexes of NSAIDs like naproxen have been shown to have greater anti-inflammatory properties than the base drug. Copper naproxen can be found as a monohydrate, and it can form complexes with other organic molecules such as nicotinyl alcohol, 3-methylpyridine, and caffeine.
Preparation Copper naproxen is prepared by reacting sodium naproxen with a copper(II) salt such as copper(II) sulfate.
2 C14H13NaO3 + CuSO4 → C28H26CuO6 + Na2SO4
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