Cytidine diphosphate glucose, often abbreviated CDP-glucose, is a nucleotide-linked sugar consisting of cytidine diphosphate and glucose. This nucleotide saccharide participates in the synthesis of deoxy sugars such as paratose and tyvelose.
Metabolism CDP-glucose is produced from CTP and glucose-1-phosphate by the enzyme glucose-1-phosphate cytidylyltransferase. CDP-glucose is an important metabolite in certain bacteria, which synthesize O antigens from it. CDP-glucose can also be used as a substrate for glycogenin, along its native substrate, UDP-glucose. The same is true for TDP-glucose.
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