Preply — Study more efficiently by working with a personal tutor. Get 50% off.Affiliate

Wikipedia

Dasolampanel

Dasolampanel

Dasolampanel (INN, USAN, code name NGX-426) is an orally bioavailable analog of tezampanel and thereby competitive antagonist of the AMPA and kainate receptors which was under development by Raptor Pharmaceuticals/Torrey Pines Therapeutics for the treatment of chronic pain conditions including neuropathic pain and migraine. It was developed as a follow-on compound to tezampanel, as tezampanel is not bioavailable orally and must be administered by intravenous injection, but ultimately neither drug was ever marketed.

See also Irampanel Selurampanel

References

Tags

  • AMPA receptor antagonists
  • Analgesic stubs
  • Analgesics
  • Antimigraine drugs
  • Carboxylic acids
  • Chlorobenzene derivatives
  • Decahydroisoquinolines
  • Drugs not assigned an ATC code
  • Kainate receptor antagonists
  • Prodrugs
  • Tetrazoles