The E-site is the third and final binding site for t-RNA in the ribosome during translation, a part of protein synthesis. The "E" stands for exit, and is accompanied by the P-site (for peptidyl) which is the second binding site, and the A-site (aminoacyl), which is the first binding site. It is involved in cellular processes.
References
Further reading Wilson, D. N.; Nierhaus, K. H. (December 2006). "The E-site story: the importance of maintaining two tRNAs on the ribosome during protein synthesis". Cellular and Molecular Life Sciences. 63 (23): 2725–2737. doi:10.1007/s00018-006-6125-4. PMC 11136154. PMID 17013564. Nierhaus, K (August 2006). "Decoding errors and the involvement of the E-site". Biochimie. 88 (8): 1013–1019. doi:10.1016/j.biochi.2006.02.009. PMID 16644089.