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Fluoroestradiol (18F)

Fluoroestradiol (18F)

Fluoroestradiol F-18, also known as [18F]16α-fluoroestradiol and sold under the brand name Cerianna, is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging. It is an analog of estrogen and is used to detect estrogen receptor-positive breast cancer lesions.

Chemistry Chemically, fluoroestradiol F-18 is [18F]16α-fluoro-3,17β-diol-estratriene-1,3,5(10).

History Fluoroestradiol F-18 was approved for medical use in the United States in May 2020.

References

External links "Fluoroestradiol F-18". NCI Thesaurus.

Tags

  • Breast cancer
  • Estradiol
  • Estranes
  • Estrogens
  • Hydroxyarenes
  • Medicinal radiochemistry
  • Organofluorides
  • PET radiotracers
  • Radiopharmaceuticals
  • Secondary alcohols