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GABBR2

GABBR2 is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand GABBR2 rather than just read about it. In short: Gamma-aminobutyric acid (GABA) B receptor, 2 (GABAB2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans. Function B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase.

GABBR2 — main illustration
GABBR2 — illustration

Key takeaways

  • GABBR2 belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect GABBR2 to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of GABBR2 from memory before moving on to harder problems.

Reference excerpt

Gamma-aminobutyric acid (GABA) B receptor, 2 (GABAB2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans.

Function B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. See GABBR1 (MIM 603540) for additional background information on GABA-B receptors.[supplied by OMIM]

Interactions GABBR2 has been shown to interact with GABBR1.

See also GABAB receptor

References

Further reading

External links "GABAB Receptors: GABAB2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Overview of all the structural information available in the PDB for UniProt: O75899 (Gamma-aminobutyric acid type B receptor subunit 2) at the PDBe-KB. This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Illustrations

GABBR2 illustration
GABBR2 illustration
GABBR2 illustration
GABBR2 illustration
GABBR2 illustration

Worked examples

Example 1 — a first encounter with GABBR2

Start with the simplest possible case. Write down what GABBR2 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to GABBR2 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about GABBR2 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of GABBR2

In research
GABBR2 appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses GABBR2 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
GABBR2 is common in secondary-school and first-year university syllabi. It links to neighbouring topics G protein-coupled receptors, Genes on human chromosome 9, Transmembrane receptor stubs, so understanding it makes those chapters shorter.
In everyday life
Look for GABBR2 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study GABBR2 in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what GABBR2 means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain GABBR2 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is GABBR2 in simple terms?

Gamma-aminobutyric acid (GABA) B receptor, 2 (GABAB2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans. Function B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which r…

Why does GABBR2 matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study GABBR2?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on GABBR2.

Tags

  • G protein-coupled receptors
  • Genes on human chromosome 9
  • Transmembrane receptor stubs

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