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GPT-4

GPT-4 is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand GPT-4 rather than just read about it. In short: Generative Pre-trained Transformer 4 (GPT-4) is a large language model developed by OpenAI and the fourth in its series of GPT foundation models. GPT-4 is preceded by GPT-3.5 and followed by its successor GPT-5.

GPT-4 — main illustration
GPT-4 — illustration

Key takeaways

  • GPT-4 belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect GPT-4 to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of GPT-4 from memory before moving on to harder problems.

Reference excerpt

Generative Pre-trained Transformer 4 (GPT-4) is a large language model developed by OpenAI and the fourth in its series of GPT foundation models. GPT-4 is preceded by GPT-3.5 and followed by its successor GPT-5. GPT-4V is a version of GPT-4 that can process images in addition to text. OpenAI has not revealed technical details and statistics about GPT-4, such as the precise size of the model. An early version of GPT-4 was integrated by Microsoft into Bing Chat, launched in February 2023. GPT-4 was released in ChatGPT in March 2023, and removed in 2025. GPT-4 is still available in OpenAI's API.

Background

OpenAI introduced the first GPT model (GPT-1) in 2018, publishing a paper called "Improving Language Understanding by Generative Pre-Training", which was based on the transformer architecture and trained on a large corpus of books. The next year, they introduced GPT-2, a larger model that could generate coherent text. In 2020, they introduced GPT-3, a model with over 100 times as many parameters as GPT-2. GPT-3 was further improved into GPT-3.5, which was used to create the chatbot product ChatGPT.

Capabilities GPT-4 was released on March 14, 2023. The default version had a 8K context window, with a special version in the API supporting up to 32K tokens. Unlike its predecessors, GPT-4 is a multimodal model: it can take images as well as text as input. It can now interact with users through spoken words and respond to images, allowing the ability to provide suggestions or answers based on photo uploads. GPT-4 can be prompted to interact with external interfaces. For example, the model could be told to enclose a query within <search></search> tags to perform a web search, the result of which would be inserted into the model's prompt to allow it to form a response. This allows the model to perform tasks beyond its normal text-prediction capabilities, such as using APIs, generating images, and accessing and summarizing webpages. A 2023 article in Nature stated programmers have found GPT-4 useful for assisting in coding tasks (despite its propensity for error), such as finding errors in existing code and suggesting optimizations to improve performance. The article quoted a biophysicist who found that the time he required to port one of his programs from MATLAB to Python went down from days to "an hour or so". On a test of 89 security scenarios, GPT-4 produced code vulnerable to SQL injection attacks 5% of the time, an improvement over GitHub Copilot from the year 2021, which produced vulnerabilities 40% of the time. In November 2023, OpenAI announced the GPT-4 Turbo and GPT-4 Turbo with Vision model, which features a 128K context window and significantly cheaper pricing.

Aptitude on standardized tests Studies have disputed the reliability of running chatbots through standardized tests. In the Torrance Tests of Creative Thinking, GPT-4 scored within the top 1% for originality and fluency, while its flexibility scores ranged from the 93rd to the 99th percentile.

Medical applications

Researchers from Microsoft tested GPT-4 on medical problems and found "that GPT-4, without any specialized prompt crafting, exceeds the passing score on USMLE by over 20 points and outperforms earlier general-purpose models (GPT-3.5) as well as models specifically fine-tuned on medical knowledge (Med-PaLM, a prompt-tuned version of Flan-PaLM 540B). Despite GPT-4's strong performance on tests, the report warns of "significant risks" of using LLMs in medical applications, as they may provide inaccurate recommendations and hallucinate major factual errors. In April 2023, Microsoft and Epic Systems announced that they will provide healthcare providers with GPT-4-powered systems for assisting in responding to questions from patients and analysing medical records.

GPT-4o

On May 13, 2024, OpenAI introduced GPT-4o ("o" for "omni"), a successor to GPT-4 that marks a significant advancement by processing and generating outputs across text, audio, and image modalities in real time. GPT-4o exhibits rapid response times comparable to human reaction in conversations, substantially improved performance on non-English languages, and enhanced understanding of vision and audio. It was also available to free-tier users, unlike GPT-4.

Limitations Like its predecessors, GPT-4 has been known to hallucinate, meaning that the outputs may include information not in the training data or that contradicts the user's prompt. GPT-4 also lacks transparency in its decision-making processes. If requested, the model is able to provide an explanation as to how and why it makes its decisions but these explanations are formed post-hoc; it's impossible to verify if those explanations truly reflect the actual process. In many cases, when asked to explain its logic, GPT-4 will give explanations that directly contradict its previous statements. In 2023, researchers tested GPT-4 against a new benchmark called ConceptARC, designed to measure abstract reasoning, and found it scored below 33% on all categories, while models specialized for similar tasks scored 60% on most, and humans scored at least 91% on all. Sam Bowman, who was not involved in the research, said the results do not necessarily indicate a lack of abstract reasoning abilities, because the test is visual, while GPT-4 is a language model.

Bias GPT-4 was trained in two stages. First, the model was given large datasets of text taken from the internet and trained to predict the next token (roughly corresponding to a word) in those datasets. Second, human reviews are used to fine-tune the system in a process called reinforcement learning from human feedback, which trains the model to refuse prompts which go against OpenAI's definition of harmful behavior, such as questions on how to perform illegal activities, advice on how to harm oneself or others, or requests for descriptions of graphic, violent, or sexual content. Microsoft researchers suggested GPT-4 may exhibit cognitive biases such as confirmation bias, anchoring, and base-rate neglect.

Training

… excerpt ends here. Continue reading the full article.

Illustrations

GPT-4 illustration
GPT-4: Evolution over one month of training of GPT-4's ability to generate TikZ code depicting a unicorn (early version of GPT-4 not trained on images)[28]
Evolution over one month of training of GPT-4's ability to generate TikZ code depicting a unicorn (early version of GPT-4 not trained on images)[28]

Worked examples

Example 1 — a first encounter with GPT-4

Start with the simplest possible case. Write down what GPT-4 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to GPT-4 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about GPT-4 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of GPT-4

In research
GPT-4 appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses GPT-4 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
GPT-4 is common in secondary-school and first-year university syllabi. It links to neighbouring topics 2023 in artificial intelligence, 2023 software, ChatGPT, so understanding it makes those chapters shorter.
In everyday life
Look for GPT-4 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study GPT-4 in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what GPT-4 means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain GPT-4 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is GPT-4 in simple terms?

Generative Pre-trained Transformer 4 (GPT-4) is a large language model developed by OpenAI and the fourth in its series of GPT foundation models. GPT-4 is preceded by GPT-3.5 and followed by its successor GPT-5.

Why does GPT-4 matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study GPT-4?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on GPT-4.

Tags

  • 2023 in artificial intelligence
  • 2023 software
  • ChatGPT
  • Generative pre-trained transformers
  • Large language models

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