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GPT-4o

GPT-4o is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand GPT-4o rather than just read about it. In short: GPT-4o ("o" for "omni") is a multilingual, multimodal generative pre-trained transformer developed by OpenAI and released in May 2024 as part of its GPT series of models. It can process and generate text, images and audio.

GPT-4o — main illustration
GPT-4o — illustration

Key takeaways

  • GPT-4o belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect GPT-4o to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of GPT-4o from memory before moving on to harder problems.

Reference excerpt

GPT-4o ("o" for "omni") is a multilingual, multimodal generative pre-trained transformer developed by OpenAI and released in May 2024 as part of its GPT series of models. It can process and generate text, images and audio. Upon release, GPT-4o was free in ChatGPT, though paid subscribers had higher usage limits. GPT-4o was removed from ChatGPT in August 2025 when GPT-5 was released, but OpenAI reintroduced it for paid subscribers after users complained about the sudden removal. GPT-4o's audio-generation capabilities were used in ChatGPT's Advanced Voice Mode. On July 18, 2024, OpenAI released GPT-4o mini, a smaller version of GPT-4o which replaced GPT-3.5 Turbo on the ChatGPT interface. The image generation model GPT Image 1, which is based on GPT-4o, replaced DALL-E 3 in ChatGPT in March 2025. OpenAI retired GPT-4o from ChatGPT on February 13, 2026, with OpenAI saying that most users had switched to GPT-5.2. The retirement applied only to ChatGPT, and GPT-4o continued to be available through the API. The separate chatgpt-4o-latest API snapshot was retired on February 17, 2026, while other GPT-4o snapshots remained available through the API.

Background Multiple versions of GPT-4o were originally secretly launched under different names on Arena (formerly LMArena and Chatbot Arena) as three different models. These three models were called gpt2-chatbot, im-a-good-gpt2-chatbot, and im-also-a-good-gpt2-chatbot. On 7 May 2024, OpenAI CEO Sam Altman tweeted "im-a-good-gpt2-chatbot", which was commonly interpreted as a confirmation that these were new OpenAI models being A/B tested.

Capabilities

When released in May 2024, GPT-4o achieved state-of-the-art results in voice, multilingual, and vision benchmarks, setting new records in audio speech recognition and translation. GPT-4o scored 88.7 on the Massive Multitask Language Understanding (MMLU) benchmark compared to 86.5 for GPT-4. Unlike GPT-3.5 and GPT-4, which rely on other models to process sound, GPT-4o natively supports voice-to-voice. The Advanced Voice Mode was delayed and finally released to ChatGPT Plus and Team subscribers in September 2024. On 1 October 2024, the Realtime API was introduced. When released, the model supported over 50 languages, which OpenAI claims cover over 97% of speakers. GPT-4o has knowledge up to October 2023 and a context length of 128k tokens.

Corporate customization In August 2024, OpenAI introduced a new feature allowing corporate customers to customize GPT-4o using proprietary company data. This customization, known as fine-tuning, enables businesses to adapt GPT-4o to specific tasks or industries, enhancing its utility in areas like customer service and specialized knowledge domains. Previously, fine-tuning was available only on the less powerful model GPT-4o mini. The fine-tuning process requires customers to upload their data to OpenAI's servers, with the training typically taking one to two hours. OpenAI's focus with this rollout is to reduce the complexity and effort required for businesses to tailor AI solutions to their needs, potentially increasing the adoption and effectiveness of AI in corporate environments.

GPT-4o mini

On July 18, 2024, OpenAI released a smaller and cheaper version, GPT-4o mini. According to OpenAI, its low cost is expected to be particularly useful for companies, startups, and developers that seek to integrate it into their services, which often make a high number of API calls. Its API costs $0.15 per million input tokens and $0.6 per million output tokens, compared to $2.50 and $10, respectively, for GPT-4o. It is also significantly more capable and 60% cheaper than GPT-3.5 Turbo, which it replaced on the ChatGPT interface. The price after fine-tuning doubles: $0.3 per million input tokens and $1.2 per million output tokens.

Controversies

Scarlett Johansson controversy As released, GPT-4o offered five voices: Breeze, Cove, Ember, Juniper, and Sky. A similarity between the voice of American actress Scarlett Johansson and Sky was quickly noticed. On May 14, Entertainment Weekly asked themselves whether this likeness was on purpose. On May 18, Johansson's husband, Colin Jost, joked about the similarity in a segment on Saturday Night Live. On May 20, 2024, OpenAI disabled the Sky voice. Scarlett Johansson starred in the 2013 sci-fi movie Her, playing Samantha, an artificially intelligent virtual assistant personified by a female voice. As part of the promotion leading up to the release of GPT-4o, Sam Altman on May 13 tweeted a single word: "her". OpenAI stated that each voice was based on the voice work of a hired actor. According to OpenAI, "Sky's voice is not an imitation of Scarlett Johansson but belongs to a different professional actress using her own natural speaking voice." CTO Mira Murati stated "I don't know about the voice. I actually had to go and listen to Scarlett Johansson's voice." OpenAI further stated the voice talent was recruited before reaching out to Johansson. On May 21, Johansson issued a statement explaining that OpenAI had repeatedly offered to make her a deal to gain permission to use her voice as early as nine months prior to release, a deal she rejected. She said she was "shocked, angered, and in disbelief that Mr. Altman would pursue a voice that sounded so eerily similar to mine that my closest friends and news outlets could not tell the difference." In the statement, Johansson also used the incident to draw attention to the lack of legal safeguards around the use of creative work to power leading AI tools, as her legal counsel demanded OpenAI detail the specifics of how the Sky voice was created. Observers noted similarities to how Johansson had previously sued and settled with The Walt Disney Company for breach of contract over the direct-to-streaming rollout of her Marvel film Black Widow, a settlement widely speculated to have netted her around $40M. Also on May 21, Shira Ovide at The Washington Post shared her list of "most bone-headed self-owns" by technology companies, with the decision to go ahead with a Johansson sound-alike voice despite her opposition and then denying the similarities ranking 6th. On May 24, Derek Robertson at Politico wrote about the "massive backlash", concluding that "appropriating the voice of one of the world's most famous movie stars — in reference [...] to a film that serves as a cautionary tale about over-reliance on AI — is unlikely to help shift the public back into [Sam Altman's] corner anytime soon."

… excerpt ends here. Continue reading the full article.

Illustrations

GPT-4o illustration

Worked examples

Example 1 — a first encounter with GPT-4o

Start with the simplest possible case. Write down what GPT-4o claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to GPT-4o before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about GPT-4o ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of GPT-4o

In research
GPT-4o appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses GPT-4o in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
GPT-4o is common in secondary-school and first-year university syllabi. It links to neighbouring topics 2024 in artificial intelligence, 2024 software, ChatGPT, so understanding it makes those chapters shorter.
In everyday life
Look for GPT-4o outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study GPT-4o in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what GPT-4o means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain GPT-4o out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is GPT-4o in simple terms?

GPT-4o ("o" for "omni") is a multilingual, multimodal generative pre-trained transformer developed by OpenAI and released in May 2024 as part of its GPT series of models. It can process and generate text, images and audio.

Why does GPT-4o matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study GPT-4o?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on GPT-4o.

Tags

  • 2024 in artificial intelligence
  • 2024 software
  • ChatGPT
  • Generative AI
  • Generative pre-trained transformers
  • Large language models
  • Text-to-image generation

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