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chemistry

GW-842,166X

GW-842,166X is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand GW-842,166X rather than just read about it. In short: GW-842,166X is a drug which acts as a potent and selective cannabinoid CB2 receptor agonist, with a novel chemical structure based on a pyrimidine core. It has potent analgesic, anti-inflammatory and anti-hyperalgesic actions in animal models, but without cannabis-like behavioural effects due to its extremely low affinity for the CB1 receptor.

GW-842,166X — main illustration
GW-842,166X — illustration

Key takeaways

  • GW-842,166X belongs to chemistry; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect GW-842,166X to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of GW-842,166X from memory before moving on to harder problems.

Reference excerpt

GW-842,166X is a drug which acts as a potent and selective cannabinoid CB2 receptor agonist, with a novel chemical structure based on a pyrimidine core. It has potent analgesic, anti-inflammatory and anti-hyperalgesic actions in animal models, but without cannabis-like behavioural effects due to its extremely low affinity for the CB1 receptor. GSK brought this compound for into 4 clinical trials, two of them related to pain management and the other two related to bio-distributions. The trials were either withdrawn or completed without posting result.

See also LY2828360

References

Illustrations

GW-842,166X illustration

Worked examples

Example 1 — a first encounter with GW-842,166X

Start with the simplest possible case. Write down what GW-842,166X claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to GW-842,166X before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about GW-842,166X ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of GW-842,166X

In research
GW-842,166X appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses GW-842,166X in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
GW-842,166X is common in secondary-school and first-year university syllabi. It links to neighbouring topics Aminopyrimidines, Cannabinoid stubs, Cannabinoids, so understanding it makes those chapters shorter.
In everyday life
Look for GW-842,166X outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study GW-842,166X in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what GW-842,166X means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain GW-842,166X out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is GW-842,166X in simple terms?

GW-842,166X is a drug which acts as a potent and selective cannabinoid CB2 receptor agonist, with a novel chemical structure based on a pyrimidine core. It has potent analgesic, anti-inflammatory and anti-hyperalgesic actions in animal models, but without cannabis-like behavioural effects due to it…

Why does GW-842,166X matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study GW-842,166X?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on GW-842,166X.

Tags

  • Aminopyrimidines
  • Cannabinoid stubs
  • Cannabinoids
  • Dichlorophenyl compounds
  • Trifluoromethyl compounds

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