Gadolinium(III) hydroxide is a chemical compound with the formula Gd(OH)3. Its nanoparticle form has potential uses for layering various drugs, such as diclofenac, ibuprofen, and naproxen.
Production and properties Gadolinium(III) hydroxide can be produced in various ways such as the reaction of gadolinium(III) nitrate and sodium hydroxide:
Gd(NO3)3 + NaOH → Gd(OH)3 + NaNO3 If this compound is heated to 307 °C, it decomposes to gadolinium(III) oxide-hydroxide(GdOOH), which in turn decomposes to gadolinium(III) oxide if continually heated.
Uses Gadolinium(III) hydroxide has no commercial uses. However, gadolinium(III) hydroxide nanoparticles have gained interest as a coating agent for various anti-inflammatory drugs such as diclofenac, ibuprofen, and naproxen due to their property to be non-cytotoxic. The nanoparticles are produced by adding base anion exchange resin to gadolinium(III) nitrate.
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