In enzymology, a glucose 1-dehydrogenase (FAD, quinone) (EC 1.1.5.9) is an enzyme that catalyzes the chemical reaction
D-glucose + a quinone ⇌ {\displaystyle \rightleftharpoons } D-glucono-1,5-lactone + a quinol Thus, the two substrates of this enzyme are D-glucose and a quinone, whereas its two products are D-glucono-1,5-lactone and a quinol. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-glucose:acceptor 1-oxidoreductase. Other names in common use include glucose dehydrogenase (Aspergillus), glucose dehydrogenase (decarboxylating), and D-glucose:(acceptor) 1-oxidoreductase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, FAD.
References
Bak TG (July 1967). "Studies on glucose dehydrogenase of Aspergillus oryzae. II. Purification and physical and chemical properties". Biochimica et Biophysica Acta (BBA) - Enzymology. 139 (2): 277–93. doi:10.1016/0005-2744(67)90032-0. PMID 6034674.
