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Glycine N-acyltransferase

Glycine N-acyltransferase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Glycine N-acyltransferase rather than just read about it. In short: Glycine N-acyltransferase (GLYAT), also known as acyl-CoA:glycine N-acyltransferase (ACGNAT), (EC 2.3.1.13) is an enzyme that catalyzes a general chemical reaction in which glycine is converted to an N-acyl derivative. glycine + an acyl-CoA ⇌ {\displaystyle \rightleftharpoons } N-acylglycine + CoA For example, glycine reacts with benzoyl-CoA to give hippuric acid: Benzoic acid is metabolized by butyrate-CoA ligase i…

Glycine N-acyltransferase — main illustration
Glycine N-acyltransferase — illustration

Key takeaways

  • Glycine N-acyltransferase belongs to engineering; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Glycine N-acyltransferase to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Glycine N-acyltransferase from memory before moving on to harder problems.

Reference excerpt

Glycine N-acyltransferase (GLYAT), also known as acyl-CoA:glycine N-acyltransferase (ACGNAT), (EC 2.3.1.13) is an enzyme that catalyzes a general chemical reaction in which glycine is converted to an N-acyl derivative.

glycine + an acyl-CoA ⇌ {\displaystyle \rightleftharpoons } N-acylglycine + CoA For example, glycine reacts with benzoyl-CoA to give hippuric acid:

Benzoic acid is metabolized by butyrate-CoA ligase into the intermediate, benzoyl-CoA, which is then metabolized by glycine N-acyltransferase into hippuric acid. The enzyme is a transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:glycine N-acyltransferase. Other names in common use include glycine acyltransferase, and glycine-N-acylase.

References

Illustrations

Glycine N-acyltransferase illustration
Glycine N-acyltransferase illustration
Glycine N-acyltransferase illustration

Worked examples

Example 1 — a first encounter with Glycine N-acyltransferase

Start with the simplest possible case. Write down what Glycine N-acyltransferase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Glycine N-acyltransferase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Glycine N-acyltransferase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Glycine N-acyltransferase

In research
Glycine N-acyltransferase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Glycine N-acyltransferase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Glycine N-acyltransferase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 2.3.1, EC 2.3 stubs, Enzymes of unknown structure, so understanding it makes those chapters shorter.
In everyday life
Look for Glycine N-acyltransferase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Glycine N-acyltransferase in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Glycine N-acyltransferase means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Glycine N-acyltransferase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Glycine N-acyltransferase in simple terms?

Glycine N-acyltransferase (GLYAT), also known as acyl-CoA:glycine N-acyltransferase (ACGNAT), (EC 2.3.1.13) is an enzyme that catalyzes a general chemical reaction in which glycine is converted to an N-acyl derivative. glycine + an acyl-CoA ⇌ {\displaystyle \rightleftharpoons } N-acylglycine + CoA…

Why does Glycine N-acyltransferase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Glycine N-acyltransferase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Glycine N-acyltransferase.

Tags

  • EC 2.3.1
  • EC 2.3 stubs
  • Enzymes of unknown structure

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