engineering

Glycine formimidoyltransferase

Glycine formimidoyltransferase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Glycine formimidoyltransferase rather than just read about it. In short: Glycine formimidoyltransferase (EC 2.1.2.4) is an enzyme that catalyzes the chemical reaction This tetrahydrofolate–dependent enzyme catalyzes a nucleophilic acyl substitution of the formimino group from the cofactor 5-formiminotetrahydrofolate to glycine, giving N-formimidoylglycine, with tetrahydrofolate (THF) as a byproduct. The enzyme can act in reverse to produce 5-formiminotetrahydrofolate.

Key takeaways

Glycine formimidoyltransferase belongs to engineering; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Glycine formimidoyltransferase to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Glycine formimidoyltransferase from memory before moving on to harder problems.

Reference excerpt

Glycine formimidoyltransferase (EC 2.1.2.4) is an enzyme that catalyzes the chemical reaction

This tetrahydrofolate–dependent enzyme catalyzes a nucleophilic acyl substitution of the formimino group from the cofactor 5-formiminotetrahydrofolate to glycine, giving N-formimidoylglycine, with tetrahydrofolate (THF) as a byproduct. The enzyme can act in reverse to produce 5-formiminotetrahydrofolate. This enzyme belongs to the family of transferases that transfer one-carbon groups, specifically the hydroxymethyl-, formyl- and related transferases. The systematic name of this enzyme class is 5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase. Other names in common use include formiminoglycine formiminotransferase, FIG formiminotransferase, and glycine formiminotransferase. This enzyme participates in purine metabolism.

References

Illustrations

Worked examples

Example 1 — a first encounter with Glycine formimidoyltransferase

Start with the simplest possible case. Write down what Glycine formimidoyltransferase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Glycine formimidoyltransferase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Glycine formimidoyltransferase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Glycine formimidoyltransferase

In research: Glycine formimidoyltransferase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Glycine formimidoyltransferase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Glycine formimidoyltransferase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 2.1.2, EC 2.1 stubs, Enzymes of unknown structure, so understanding it makes those chapters shorter.
In everyday life: Look for Glycine formimidoyltransferase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Glycine formimidoyltransferase in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Glycine formimidoyltransferase means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Glycine formimidoyltransferase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Glycine formimidoyltransferase in simple terms?

Glycine formimidoyltransferase (EC 2.1.2.4) is an enzyme that catalyzes the chemical reaction This tetrahydrofolate–dependent enzyme catalyzes a nucleophilic acyl substitution of the formimino group from the cofactor 5-formiminotetrahydrofolate to glycine, giving N-formimidoylglycine, with tetrahyd…

Why does Glycine formimidoyltransferase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Glycine formimidoyltransferase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Glycine formimidoyltransferase.