Glycochenodeoxycholate sulfotransferase (EC 2.8.2.34) is an enzyme that catalyzes the chemical reaction
The enzyme characterised from hamsters uses the cofactor 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to convert the bile acid, glycochenodeoxycholic acid, to its sulfate derivative, giving adenosine 3',5'-bisphosphate as a byproduct.
Nomenclature This enzyme is a transferase, specifically a sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase. Other names in common use include bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase, bile acid:PAPS:sulfotransferase, and BAST.
See also Bile salt sulfotransferase which acts on a wider range of substrates in a similar reaction
References



