In enzymology, a glycosaminoglycan galactosyltransferase (EC 2.4.1.74) is an enzyme that catalyzes the chemical reaction
UDP-galactose + glycosaminoglycan ⇌ {\displaystyle \rightleftharpoons } UDP + D-galactosylglycosaminoglycan Thus, the two substrates of this enzyme are UDP-galactose and glycosaminoglycan, whereas its two products are UDP and D-galactosylglycosaminoglycan. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:glycosaminoglycan D-galactosyltransferase. This enzyme is also called uridine diphosphogalactose-mucopolysaccharide galactosyltransferase.
References
Sussman M, Osborn MJ (1964). "UDP-glucose polysaccharide transferase in the cellular slime mold Dictyostelium discoideum: appearance and disappearance of activity during cell differentiation". Proc. Natl. Acad. Sci. USA. 52 (1): 81–87. Bibcode:1964PNAS...52...81S. doi:10.1073/pnas.52.1.81. PMC 300577. PMID 14192661.
