Histone deacetylase 10 is an enzyme that in humans is encoded by the HDAC10 gene. HDAC10 is a class IIb HDAC. It specifically has selectivity for long, slender polyamines like N8-acetylspermidine. Acetylation of histone core particles modulates chromatin structure and gene expression. The opposing enzymatic activities of histone acetyltransferases and histone deacetylases, such as HDAC10, determine the acetylation status of histone tails (Kao et al., 2002).[supplied by OMIM]
Interactions HDAC10 has been shown to interact with Histone deacetylase 2 and Nuclear receptor co-repressor 2.
See also Histone deacetylase
References
Further reading
External links HDAC10+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine, which is in the public domain.





