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Haplogroup M8

Haplogroup M8 is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Haplogroup M8 rather than just read about it. In short: In human mitochondrial genetics, Haplogroup M8 is a human mitochondrial DNA (mtDNA) haplogroup. Origin Haplogroup M8 is a descendant of haplogroup M.

Key takeaways

  • Haplogroup M8 belongs to science; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Haplogroup M8 to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Haplogroup M8 from memory before moving on to harder problems.

Reference excerpt

In human mitochondrial genetics, Haplogroup M8 is a human mitochondrial DNA (mtDNA) haplogroup.

Origin Haplogroup M8 is a descendant of haplogroup M. Haplogroup M8 is divided into subclades M8a, C and Z.

Distribution It is an East Asian haplogroup. Today, haplogroup M8 is found at its highest frequency in indigenous populations of East Siberia such as Evenk and Yukaghir. Haplogroup M8 is one of the most common mtDNA haplogroups among Yakut, Tuvan. Haplogroup C, the most major one of three subclades, is highly distributed among the Amerindian and Indigenous peoples of East Siberia. Haplogroup Z, another one of three subclades, is highly distributed among Even from Kamchatka (8/39 Z1a2a, 3/39 Z1a3, 11/39 = 28.2% Z total). mtDNA Haplogroup M8a, a not well known one of the three subclades, is highly distributed among Northern Han Chinese from Liaoning (16/317 = 5.0%).

Table of Frequencies by ethnic group

Subclades Haplogroup C, the most major one of three subclades is highly distributed among the Amerindian and Indigienous peoples of East Siberia. Haplogroup Z, the other one of three subclades is highly distributed among Even from Kamchatka (8/39 Z1a2a, 3/39 Z1a3, 11/39 = 28.2% Z total), mtDNA Haplogroup M8a, not well known one of three subclades is highly distributed among Northern Han Chinese from Liaoning (16/317 = 5.0%).

Tree This phylogenetic tree of haplogroup M8 subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research.

M8 M8a M8a1 - Ulch M8a1a - Japanese M8a2'3 M8a2 - Japanese, Han Chinese M8a2-a* - Japanese, Russia M8a2a'b (T152C!) - Japanese M8a2a - Han Chinese M8a2a1 - Japanese, Han Chinese(Hunan) M8a2a1a1 M8a2a1b M8a2a1c - Japanese M8a2b - Japanese, Han Chinese (Shandong) M8a2b1 M8a2b2 - Russia M8a2c - Japanese, Han Chinese M8a2d - Han Chinese M8a2e - Ami(Taiwan Aborigines), Han Chinese (Taiwan) M8a3 - Japanese, Han Chinese M8a3a - Han Chinese M8a3a1 - Han Chinese CZ C C1 C1a - Ulch, Swedish C1b - Amerindian C1b1 C1b2 C1b3 C1b4 C1b5 C1b5a C1b5b C1b6 C1b7'10 (T16311C!) C1b7 C1b7a C1b10 C1b8 C1b9 C1b11 C1b12 C1b13 C1b13a C1b13a1 C1b13b C1b13c C1b13c1 C1b13d C1b13e C1b14 C1c - Amerindian C1c1 C1c1a C1c1b C1c2 C1c3 C1c4 C1c5 C1c6'7 C1c6 C1c7 C1c8 C1d - Amerindian C1d1 C1d1a C1d1a1 C1d1b C1d1b1 C1d1c C1d1c1 C1d1d C1d2 C1d2a C1d3 C1e - Amerindian C1f - Amerindian C4 - Siberian, Mongolian, Han Chinese C4a'b'c C4a C4a1 C4a1a C4a1a1 C4a1a1a C4a1a2'3'4 C4a1a2 C4a1a2a C4a1a3 C4a1a3a C4a1a3a1 C4a1a3b C4a1a3c C4a1a3d C4a1a4 C4a1a4a C4a1a5 C4a1a6 C4a2 C4a2a C4a2a1 C4a2a1a C4a2a1b C4a2b C4a2b1 C4a2b2 C4a2b2a C4a2c C4a2c1 C4a2c2 C4a2c2a C4b C4b1 C4b1a C4b1b C4b2 C4b2a C4b3 C4b3a C4b3a1 C4b3b C4b5 C4b6 C4b7 C4b8 C4b8a C4c C4c1 C4c1a C4c1b C4c2 C4d'e C4d C4e C5 - Siberian, Mongolian, Han Chinese C5a C5a1 C5a2 C5a2a C5a2b C5a2b1 C5b C5b1 C5b1a C5b1a1 C5b1b C5b1b1 C5c'd C5c C5c1 C5c1a C5d C5d1 C5d2 C7 - Han Chinese, Indo-China Peninsulan C7a C7a1 C7a1a C7a1a1 C7a1a2 C7a1c C7a1d C7a2 C7a2a C7b Z Z1'2'3'4'7 Z1 - Tofalar Z1a - Tubalar Z1a1 Z1a1a - Saami, Kets Z1a1b - Nganasan, Estonian Z1a2 - Ulch Z1a2a - Nivkh Z1a3 - Yakuts, Estonian Z2 - Japanese Z3 - Japanese Z3a Z3a1 Z3a1a - Han Chinese, Indian Z3a2 - Indian Z3b - Indian Z3c - Persian(Iranian), Japanese Z3d - Han Chinese, Taiwanese Z4 - Han Chinese Z4a - Japanese Z4a1 - Han Chinese Z4a1a Z4a1a1 - Japanese Z7 - Indian Z5 - Japanese

Popular culture The American figure skater Kristi Yamaguchi is a member of haplogroup M8a.

See also

Genealogical DNA test Genetic Genealogy Human mitochondrial genetics Population Genetics Human mitochondrial DNA haplogroups Indigenous American genetic studies

References

Bibliography

External links General Mannis van Oven's Phylotree Haplogroup M8 Ian Logan's Mitochondrial DNA Site: Haplogroup M8 FamilyTreeDNA's Discover: mtDNA Haplogroup M8 YFull MTree's Haplogroup M8 mitoLEAF's Haplogroup M8

Worked examples

Example 1 — a first encounter with Haplogroup M8

Start with the simplest possible case. Write down what Haplogroup M8 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Haplogroup M8 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Haplogroup M8 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Haplogroup M8

In research
Haplogroup M8 appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Haplogroup M8 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Haplogroup M8 is common in secondary-school and first-year university syllabi. It links to neighbouring topics Bioinformatics, Human mtDNA haplogroups, so understanding it makes those chapters shorter.
In everyday life
Look for Haplogroup M8 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Haplogroup M8 in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Haplogroup M8 means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Haplogroup M8 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Haplogroup M8 in simple terms?

In human mitochondrial genetics, Haplogroup M8 is a human mitochondrial DNA (mtDNA) haplogroup. Origin Haplogroup M8 is a descendant of haplogroup M.

Why does Haplogroup M8 matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Haplogroup M8?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Haplogroup M8.

Tags

  • Bioinformatics
  • Human mtDNA haplogroups

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