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Hartmut Oschkinat

Hartmut Oschkinat is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Hartmut Oschkinat rather than just read about it. In short: Hartmut Oschkinat (born 28 February 1957) is a German structural biologist and professor for chemistry at the Free University of Berlin. His research focuses on the study of biological systems with solid-state nuclear magnetic resonance.

Hartmut Oschkinat — main illustration
Hartmut Oschkinat — illustration

Key takeaways

  • Hartmut Oschkinat belongs to chemistry; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Hartmut Oschkinat to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Hartmut Oschkinat from memory before moving on to harder problems.

Reference excerpt

Hartmut Oschkinat (born 28 February 1957) is a German structural biologist and professor for chemistry at the Free University of Berlin. His research focuses on the study of biological systems with solid-state nuclear magnetic resonance. He is a member of the Editorial Boards of the Journal of Biomolecular NMR and Structure.

Life and career Oschkinat studied chemistry at the Johann-Wolfgang-Goethe University of Frankfurt. He received his doctoral degree in 1986 under the supervision of Horst Kessler with the title "Analysis of the conformation of Cyclosporin in solution using NMR-spectroscopy: development and use of new methods." in the field of nuclear magnetic resonance spectroscopy (NMR). After his work as a postdoctoral researcher with Geoffrey Bodenhausen at the University of Lausanne, Oschkinat moved to the Max Planck Institute of Biochemistry in Martinsried in 1987 as a post-doc in the Lab of Marius Clore and Angela Gronenborn. There, he was working with Marius Clore, Angela Gronenborn and the Nobel laureate Robert Huber. After his habilitation at the Technical University of Munich in 1992, Hartmut Oschkinat moved to the European Molecular Biology Laboratory in Heidelberg. Since 1998, he is the head of the department NMR-supported Structural Biology at the Leibniz-Institut für Molekulare Pharmakologie in Berlin.

Research At the beginning of his career, Oschkinat worked in the field of solution-state NMR, and made fundamental contributions to establish the role of multidimensional NMR spectroscopy in structural biology. After using solution-state NMR spectroscopy to determine three-dimensional structures of soluble proteins such as the pleckstrin homology domain and the WW domain, characterise protein–protein interactions involving the latter, with applications in fragment-based drug discovery, he moved on to focus on the investigation of biological systems by solid-state NMR (ssNMR) with magic angle spinning. His group was the first to solve a protein structure using ssNMR; the structure solved was that of a microcrystalline preparation of a SH3 domain. Since 2005, his research group investigates complex biomolecular systems such as membrane proteins within the native lipid environment, amyloid fibrils, and oligomers. Moreover, he develops methods to address challenging questions in structural biology where ssNMR can be applied with particular advantages, and have made particular contributions to the development of dynamic nuclear polarisation and proton detection using fast magic angle spinning.

Notable Achievements 1998: elected to membership of the European Molecular Biology Organization. 2009–2011: Acting Director of the Leibniz-Institut für Molekulare Pharmakologie. 2012: International Scientific Review Board for the Central European Institute of Technology in Brno, Czech Republic. 2013: elected to honorary membership of the National Magnetic Resonance Society of India. 2014: one of six awardees of the Günther Laukien Prize, awarded annually at the Experimental Nuclear Magnetic Resonance Conference in the USA.

References

External links Hartmut Oschkinat publications indexed by Google Scholar

Illustrations

Hartmut Oschkinat illustration

Worked examples

Example 1 — a first encounter with Hartmut Oschkinat

Start with the simplest possible case. Write down what Hartmut Oschkinat claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Hartmut Oschkinat before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Hartmut Oschkinat ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Hartmut Oschkinat

In research
Hartmut Oschkinat appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Hartmut Oschkinat in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Hartmut Oschkinat is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1957 births, 20th-century German biologists, 20th-century German chemists, so understanding it makes those chapters shorter.
In everyday life
Look for Hartmut Oschkinat outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Hartmut Oschkinat in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Hartmut Oschkinat means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Hartmut Oschkinat out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Hartmut Oschkinat in simple terms?

Hartmut Oschkinat (born 28 February 1957) is a German structural biologist and professor for chemistry at the Free University of Berlin. His research focuses on the study of biological systems with solid-state nuclear magnetic resonance.

Why does Hartmut Oschkinat matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Hartmut Oschkinat?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Hartmut Oschkinat.

Tags

  • 1957 births
  • 20th-century German biologists
  • 20th-century German chemists
  • 21st-century German chemists
  • German biophysicists
  • Goethe University Frankfurt alumni
  • Living people

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