biology

Harvey M. Patt

Harvey M. Patt is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Harvey M. Patt rather than just read about it. In short: Harvey Milton Patt (August 2, 1918 – November 4, 1982) was an American physiologist, radiation biologist, and cell biologist, who made "important scientific contributions in cell cycle kinetics and tissue repopulation." Education and career Patt received in 1942 his Ph.D. in physiology from the University of Chicago. His dissertation is titled The relation of a low blood calcium to parathyroid secretion.

Key takeaways

Harvey M. Patt belongs to biology; place it in that map before memorising details.
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Reference excerpt

Harvey Milton Patt (August 2, 1918 – November 4, 1982) was an American physiologist, radiation biologist, and cell biologist, who made "important scientific contributions in cell cycle kinetics and tissue repopulation."

Education and career Patt received in 1942 his Ph.D. in physiology from the University of Chicago. His dissertation is titled The relation of a low blood calcium to parathyroid secretion. He was an instructor in physiology at the University of Chicago after serving for two years as a lieutenant J.G. in the United States Navy. At Argonne National Laboratory, Patt became a staff member in 1946 and a senior physiologist in 1952. He was the executive secretary of the Oberlin Conference on Radiobiology, which was held from June 14 to June 18, 1950 and was sponsored by the National Research Council of the National Academy of Sciences. The conference dealt with "4 aspects of radiobiological interest, namely the physical, chemical, biochemical, and organismal, with the visible cellular effects included in the latter." He was an important pioneer of the field of radiobiology. As a member of the Radiation Research Society, he was the first treasurer, the ninth president, and an editorial board member of the journal Radiation Research, as well as the executive secretary of the First International Congress of Radiation Research; the congress was held in Burlington, Vermont from the 11th to the 15th of August, 1958. At the University of California, San Francisco (UCSF), Patt was appointed in 1964 the director of the Laboratory of Radiobiology and a professor of radiobiology and experimental radiology. As the successor to Robert Spencer Stone (1895–1966), he developed the program with format still used at UCSF. In 1964 Patt was awarded the Ernest Orlando Lawrence Award from the Atomic Energy Commission "for exceptionally high quality research in radiobiology, especially in the field of radiation protection and for his important contributions to the present understanding of the dynamics of white blood cells formation." In February 1964 at UCSF, Mortimer J. Elkind gave the inaugural Harvey M. Patt Memorial Lecture; after the lecture a plaque in memory of Patt was dedicated at UCSF's Laboratory of Radiobiology and Environmental Health.

Selected publications Patt, H. M.; Luckhardt, A. B. "Relation of a low blood calcium to a parathyroid secretion". Endocrinology. 31: 384–392. doi:10.1210/endo-31-3-384. (Arno B. Luckhardt (1885–1957) was a professor of physiology at the University of Chicago.) Patt, H. M.; Swift, M. N.; Tyree, E. B.; John, E. S. (1947). "Adrenal Response to Total Body X-Radiation". American Journal of Physiology. Legacy Content. 150 (3): 480–487. doi:10.1152/ajplegacy.1947.150.3.480. hdl:2027/mdp.39015095101898. PMID 20265847. (Marguerite N. Swift was a physiologist who worked on the Manhattan Project. She was one of the seventy signers of the Szilárd petition.) Patt, Harvey M.; Swift, Marguerite N. (1948). "Influence of Temperature on the Response of Frogs to X Irradiation". American Journal of Physiology. Legacy Content. 155 (3): 388–393. doi:10.1152/ajplegacy.1948.155.3.388. PMID 18113178. Patt, H. M.; Tyree, E. B.; Straube, R. L.; Smith, D. E. (1949). "Cysteine Protection against X Irradiation". Science. 110 (2852): 213–214. Bibcode:1949Sci...110..213P. doi:10.1126/science.110.2852.213. PMID 17811258. (over 950 citations) Patt, H. M.; Straube, R. L.; Tyree, E. B.; Swift, M. N.; Smith, D. E. (1949). "Influence of Estrogens on the Acute X-Irradiation Syndrome". American Journal of Physiology. Legacy Content. 159 (2): 269–280. doi:10.1152/ajplegacy.1949.159.2.269. PMID 15393468. Patt, H. M.; Smith, D. E.; Tyree, E. B.; Straube, R. L. (1950). "Further Studies on Modification of Sensitivity to X-rays by Cysteine". Experimental Biology and Medicine. 73 (1): 18–21. doi:10.3181/00379727-73-17561. PMID 15409471. S2CID 9800298. Patt, Harvey M. (1953). "Protective Mechanisms in Ionizing Radiation Injury". Physiological Reviews. 33 (1): 35–76. doi:10.1152/physrev.1953.33.1.35. PMID 13013832. Patt, H. M.; Clark, J. W.; Vogle, H. H. (1953). "Comparative Protective Effect of Cysteine against Fast Neutron and Gamma Irradiation in Mice". Experimental Biology and Medicine. 84 (1): 189–193. doi:10.3181/00379727-84-20586. PMID 13120981. S2CID 13513498. Patt, Harvey M.; Blackford, Margaret E. (1954). "Quantitative studies of the growth response of the Krebs ascites tumor". Cancer Research. 14 (5): 391–396. PMID 13160969. 1954 Patt, Harvey M.; Quastler, Henry (1963). "Radiation Effects on Cell Renewal and Related Systems". Physiological Reviews. 43 (3): 357–396. doi:10.1152/physrev.1963.43.3.357. PMID 13941891. Lala, Peeyush K.; Patt, Harvey M. (1966). "Cytokinetic Analysis of Tumor Growth". Proceedings of the National Academy of Sciences. 56 (6): 1735–1742. Bibcode:1966PNAS...56.1735L. doi:10.1073/pnas.56.6.1735. PMC 220164. PMID 16591413. (Peeyush Lala won the 2020 Henry Gray Award from the American Association for Anatomy.) Patt, H. M.; Maloney, M. A. (1972). "Bone Formation and Resorption as a Requirement for Marrow Development". Experimental Biology and Medicine. 140 (1): 205–207. doi:10.3181/00379727-140-36426. PMID 4555913. S2CID 41660190. Patt, H. M.; Maloney, M. A. (1975). "Bone marrow regeneration after local injury: A review". Experimental Hematology. 3 (2): 135–148. PMID 1095381. Patt, H. M.; Maloney, M. A.; Flannery, M. L. (1982). "Hematopoietic microenvironment transfer by stromal fibroblasts derived from bone marrow varying in cellularity". Experimental Hematology. 10 (9): 738–742. PMID 6129153.

References

External links "Patt, Harvey M., 1918–1982; Papers, 1949–1982; University of California at San Francisco, Special Collections Library" (PDF). Office of Scientific and Technical Information (osti.gov). "photo of Harvey M. Patt, September 1, 1949". myrecordjournal.com.

Illustrations

Worked examples

Example 1 — a first encounter with Harvey M. Patt

Start with the simplest possible case. Write down what Harvey M. Patt claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Harvey M. Patt before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Harvey M. Patt ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Harvey M. Patt

In research: Harvey M. Patt appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Harvey M. Patt in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Harvey M. Patt is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1918 births, 1982 deaths, American cell biologists, so understanding it makes those chapters shorter.
In everyday life: Look for Harvey M. Patt outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Harvey M. Patt in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Harvey M. Patt means in your own words.
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Frequently asked questions

What is Harvey M. Patt in simple terms?

Why does Harvey M. Patt matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Harvey M. Patt?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Harvey M. Patt.