Helicobacter hepaticus is a bacterium in the Helicobacteraceae family, Campylobacterales order. It has a spiral shape and bipolar, single, sheathed flagellum. The bacterium was first isolated from the livers of mice with active, chronic hepatitis. Other organs the bacterium colonize include the cecal and colonic mucosae of mice. It elicits persistent hepatitis in mice and has been associated with colorectal cancer and other diseases. Its genome has been sequenced and is 1,799,146 bases long with 1,875 coding sequences.
References
Further reading Kostomitsopoulos N, Donnelly H, Kostavasili I, Paronis E, Alexakos P, Karayannacos P (May 2007). "Eradication of Helicobacter bilis and H. hepaticus from infected mice by using a medicated diet". Lab Animal. 36 (5): 37–40. doi:10.1038/laban0507-37. PMID 17450169. S2CID 26505981. Hamada T, Yokota K, Ayada K, et al. (December 2009). "Detection of Helicobacter hepaticus in human bile samples of patients with biliary disease". Helicobacter. 14 (6): 545–51. doi:10.1111/j.1523-5378.2009.00729.x. PMC 2779990. PMID 19889072. Avenaud P, Le Bail B, Mayo K, et al. (June 2003). "Natural history of Helicobacter hepaticus infection in conventional A/J mice, with special reference to liver involvement". Infection and Immunity. 71 (6): 3667–72. doi:10.1128/iai.71.6.3667-3672.2003. PMC 155737. PMID 12761159. Foltz CJ, Fox JG, Yan L, Shames B (June 1995). "Evaluation of antibiotic therapies for eradication of Helicobacter hepaticus". Antimicrobial Agents and Chemotherapy. 39 (6): 1292–4. doi:10.1128/aac.39.6.1292. PMC 162729. PMID 7574518.
External links "Helicobacter hepaticus". The Encyclopedia of Life. Type strain of Helicobacter hepaticus at BacDive - the Bacterial Diversity Metadatabase
