The search for a hypothetical soul and its location have been a subject of much speculation throughout history. In early medicine and anatomy, the location of the soul was hypothesized to be located within the body. Aristotle and Plato understood the soul as an incorporeal form but closely related to the physical world. The Hippocratic Corpus chronicles the evolution of thought that the soul is located within the body and is manifested in diseased conditions. Later, Galen explicitly used Plato's description of the incorporeal soul to physical locations in the body. The logical (λογιστικός) in the brain, the spirited (θυμοειδές) in the heart, and the appetitive (ἐπιθυμητικόν) in the liver. Da Vinci had a similar approach to Galen, locating the soul, or senso comune, as well as the imprensiva (intellect) and memoria (memory) in different ventricles of the brain. Today neuroscientists and other fields of science that deal with the body and the mind, such as psychology, bridge the gap between what is physical and what is incorporeal.
Ancient Egypt
The earliest known theory pertaining to the location of the soul is thought to come from Ancient Egypt during the third millennium BCE. Ancient Egyptian civilizations held the belief that the soul was composed of several parts: the Ba, Ka, Ren, Sheut, and the Ib. Furthermore, the Ib was located in the heart, and considered the vital force that brought human beings to life. Because the Ib was also responsible for thoughts and feelings, its status determined a person's fate upon their death. This took place during a heart weighing ceremony, in which Anubis would feed the heaviest hearts to the demon Ammit. It is believed that the Ancient Egyptian view of the heart formed the foundation for later theories on the location for the human soul.
Hippocratic Corpus The Hippocratic Corpus and its many treatises demonstrate the evolving knowledge of the body and how to treat ailments in reference to the soul. In the treatise on Diseases II, physicians are warned about the illnesses associated with air in the body, particularly in the lungs causing the patient to cough vigorously and hoarsely: "διαπνειν δοΚει δια στηθεοζ", translated as "the patient is breathing through their lungs". The next lines detail that this was an extremely serious condition for the patient and a cause for great concern. To remedy air in the lungs, the physician was advised to clear the lungs of as much air as possible using a bladder and hose. Later in the Corpus, during or after the life of Aristotle on Disease IV, pneuma, or air is presented as a warming life force. In the treatise On the Sacred Disease air is described as not being located in just the lungs but in the entire body and circulating it giving life. According to the treatise the first location of the air is to the brain and it describes that medical conditions of the brain can be caused by a blockage of air flow there. Aristotle in his works refers to pneuma being directly related to the soul.
Plato
Plato, the student of Socrates and teacher to Aristotle, suggests in Timmeus that the human soul was divine in nature, and that it entered the human body after separating from a spiritual origin that it would return to upon death. Furthermore, Plato believed the soul to be a tripartite one, composed of the logos, the thymos, and the epithemitikon. In order to protect the immortal soul from contamination, the perishable souls, the thymos and the epithemitikon, were separated from the head by the neck. The thymos, responsible for feelings such as rage, bravery, and hope, was located in the chest cavity. The epithemitikon, which controlled desires and unconscious thought, was located near the umbilicus, farthest from the logos. The brain, then, was the seat of all rational thought, the logos, and the true location of the immortal and divine soul.
Aristotle In De Spiritu Aristotle links the idea of pneuma and the soul directly together saying that "Pneuma is connected to the soul" that, "it is the souls primary driving force". Aristotle in De Anima (On the Soul) suggests that organs of the body are required for the soul to interact with. Unlike Plato, Aristotle believed the soul's existence was not separate from the human body, thus the soul could not be immortal. Similarly to Plato, however, Aristotle believed the soul is composed of three parts: the vegetative, sensitive, and rational. Growth and reproduction is a result of the vegetative soul, and is found in all organisms. The sensitive soul, however, allows for sensation and movement in humans and animals. The third, the rational, is exclusive to humans, and allows for rational thought. In book II, Aristotle states that, the soul is the part of the human that allows its entire being, that one can't exist without the other and they complement each other. In book III he provides an example of his theory of the soul and makes the correlation between the physical sensations of light the phaos in the body and the incorporeal imaginations phantasia. Aristotle imagined the soul as in part, within the human body and in part an incorporeal imagination. In Aristotle's treatise On Youth, Old Age, Life and Death, and Respiration, Aristotle explicitly states that while the soul has an incorporeal form, there is a physical area of the soul in the human body, the heart. Aristotle states the heart is the location of the 5 sensations of the body and is directly responsible for respiration and the sustenance of life. The heart is of further importance as it is all animal's area of heating the body and blood and the creation of pneuma, or life force that animates the body. To Aristotle this explains why dead things become cold, do not breathe, and that their souls have left them. Because the heart is the location of the human soul and life force, it is the organ of utmost importance in Aristotelian physiology. Correspondingly, the heart is the first organ to appear during embryonic development.
Epicurus Epicurus, with a view reflecting that of the Greek philosopher Democritus, suggested that the human soul was corporeal and composed of small particles spread out within the entire body. Epicurus believed that the separation of these small particles resulted in a loss of sensation, and consequently, death. Like Aristotle, Epicurus was of the opinion that the soul was a result of the body, making it mortal and perishable.
Herophilus
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