chemistry

Homarylamine

Homarylamine is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Homarylamine rather than just read about it. In short: Homarylamine (INNTooltip International Nonproprietary Name), also known as 3,4-methylenedioxy-N-methylphenethylamine (MDMPEA) or as METHYL-H, is a chemical compound of the phenethylamine and methylenedioxyphenethylamine (MDxx) family. It is the N-methyl derivative of homopiperonylamine (methylenedioxyphenethylamine; MDPEA; H).

Key takeaways

Homarylamine belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Homarylamine to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Homarylamine from memory before moving on to harder problems.

Reference excerpt

Homarylamine (INNTooltip International Nonproprietary Name), also known as 3,4-methylenedioxy-N-methylphenethylamine (MDMPEA) or as METHYL-H, is a chemical compound of the phenethylamine and methylenedioxyphenethylamine (MDxx) family. It is the N-methyl derivative of homopiperonylamine (methylenedioxyphenethylamine; MDPEA; H). The drug was patented by Merck & Co. in 1956 and studied as an antitussive (cough suppressant) in 1961. It is a schedule I drug in the United States as a positional isomer of 3,4-methylenedioxyamphetamine (MDA).

Use and effects Homarylamine was briefly mentioned by Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved). According to Shulgin, homarylamine has been reported to be active as an antitussive (cough suppressant) at a dose of 30 mg. No central effects were described as this dose. Shulgin tried this dose and experienced a little tightness of facial muscles, but no mental effects whatsoever.

Chemistry

Reactions Reaction of homarylamine with formaldehyde gives hydrastinine. A practical application of homarylamine is in the synthesis of Roemerin.

Analogues Analogues of homarylamine include homopiperonylamine (MDPEA), lobivine (MDDMPEA), lophophine (MMDPEA), MDA, MDMA, hydrastine, and hydrastinine, among others.

See also Substituted methylenedioxyphenethylamine

References

External links METHYL-MDPEA - Isomer Design

Illustrations

Worked examples

Example 1 — a first encounter with Homarylamine

Start with the simplest possible case. Write down what Homarylamine claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Homarylamine before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Homarylamine ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Homarylamine

In research: Homarylamine appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Homarylamine in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Homarylamine is common in secondary-school and first-year university syllabi. It links to neighbouring topics Antitussives, Methyl compounds, Methylenedioxyphenethylamines, so understanding it makes those chapters shorter.
In everyday life: Look for Homarylamine outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Homarylamine in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Homarylamine means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Homarylamine out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Homarylamine in simple terms?

Why does Homarylamine matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Homarylamine?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Homarylamine.