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Homoserine/threonine resistance transporter

Homoserine/threonine resistance transporter is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Homoserine/threonine resistance transporter rather than just read about it. In short: The resistance to homoserine/threonine (RhtB) family (TC# 2.A.76) belongs to the lysine exporter (LysE) superfamily of transporters. Hundreds of sequenced proteins, derived from Gram-negative and Gram-positive bacteria as well as archaea, comprise the RhtB family, but few of these proteins are functionally characterized.

Key takeaways

  • Homoserine/threonine resistance transporter belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Homoserine/threonine resistance transporter to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Homoserine/threonine resistance transporter from memory before moving on to harder problems.

Reference excerpt

The resistance to homoserine/threonine (RhtB) family (TC# 2.A.76) belongs to the lysine exporter (LysE) superfamily of transporters. Hundreds of sequenced proteins, derived from Gram-negative and Gram-positive bacteria as well as archaea, comprise the RhtB family, but few of these proteins are functionally characterized.

Members The first two members of the RhtB family to be characterized functionally were the RhtB (TC# 2.A.76.1.1) and RhtC (TC# 2.A.76.1.2) permeases of E. coli. E. coli possesses five paralogues, and a large region of one of them (YahN of E. coli; TC# 2.A.76.1.3) exhibits significant sequence similarity to YggA of E. coli (TC# 2.A.75.1.2), an established member of the LysE family (TC #2.A.75). The PSI-BLAST program groups the LysE family (TC# 2.A.75), the RhtB family and the CadD family (TC #2.A.77) together. These proteins are all of about the same size and apparent topology, further suggesting a common evolutionary origin. The leucine exporter homologue (YeaS or LeuE; TC# 2.A.76.1.5) exports leucine and several other neutral, hydrophobic amino acids. A representative list of proteins belonging to the RhtB family can be found in the Transporter Classification Database.

General transport reaction The transport reaction presumably catalyzed by members of the RhtB family is: amino acid (in) + nH+ (out) ⇌ amino acid (out) + nH+ (in)

See also Biology portal

References

As of 25 February 2016, this article is derived in whole or in part from Transporter Classification Database, authored by Saier Lab Bioinformatics. The copyright holder has licensed the content in a manner that permits reuse under CC BY-SA 3.0 and GFDL. All relevant terms must be followed. The original text was at "2.A.76 The Resistance to Homoserine/Threonine (RhtB) Family"

Worked examples

Example 1 — a first encounter with Homoserine/threonine resistance transporter

Start with the simplest possible case. Write down what Homoserine/threonine resistance transporter claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Homoserine/threonine resistance transporter before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Homoserine/threonine resistance transporter ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Homoserine/threonine resistance transporter

In research
Homoserine/threonine resistance transporter appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Homoserine/threonine resistance transporter in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Homoserine/threonine resistance transporter is common in secondary-school and first-year university syllabi. It links to neighbouring topics Protein families, Solute carrier family, so understanding it makes those chapters shorter.
In everyday life
Look for Homoserine/threonine resistance transporter outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Homoserine/threonine resistance transporter in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Homoserine/threonine resistance transporter means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Homoserine/threonine resistance transporter out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Homoserine/threonine resistance transporter in simple terms?

The resistance to homoserine/threonine (RhtB) family (TC# 2.A.76) belongs to the lysine exporter (LysE) superfamily of transporters. Hundreds of sequenced proteins, derived from Gram-negative and Gram-positive bacteria as well as archaea, comprise the RhtB family, but few of these proteins are func…

Why does Homoserine/threonine resistance transporter matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Homoserine/threonine resistance transporter?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Homoserine/threonine resistance transporter.

Tags

  • Protein families
  • Solute carrier family

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