Hydroxybutyrate-dimer hydrolase (EC 3.1.1.22) is an enzyme that catalyzes the reaction
The enzyme characterised from Pseudomonas lemoignei hydrolyses a dimer of (R)-3-hydroxybutyric acid back to the monomer. The gene for this enzyme has been cloned for sequencing. The enzyme is also found in Zoogloea ramigera. This enzyme is a hydrolase, specifically one acting on carboxylic ester bonds. The systematic name is (R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase. The enzyme is also called D-(–)-3-hydroxybutyrate-dimer hydrolase.
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