In enzymology, a hydroxymalonate dehydrogenase (EC 1.1.1.167) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are tartronic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are mesoxalic acid, reduced NADH, and a proton. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hydroxymalonate:NAD+ oxidoreductase.
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