science

Hydroxyphenamate

Hydroxyphenamate is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Hydroxyphenamate rather than just read about it. In short: Hydroxyphenamate or oxyfenamate (trade name Listica) is a sedative and anxiolytic drug of the carbamate class which is no longer marketed in the US. Like other carbamate sedatives, it is chemically related to meprobamate (Miltown).

Key takeaways

Hydroxyphenamate belongs to science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Hydroxyphenamate to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Hydroxyphenamate from memory before moving on to harder problems.

Reference excerpt

Hydroxyphenamate or oxyfenamate (trade name Listica) is a sedative and anxiolytic drug of the carbamate class which is no longer marketed in the US. Like other carbamate sedatives, it is chemically related to meprobamate (Miltown). It was introduced to the US market in 1961. The dosage for adults is 200 mg 3 to 4 times daily.

Synthesis The reaction of propiophenone (1) with cyanide gives 2-hydroxy-2-phenylbutanenitrile (2). Acid hydrolysis of the nitrile to a carboxylic acid gives 2-hydroxy-2-phenylbutanoic acid (3). The reduction by hydride of the acid to the alcohol gives 2-phenyl-1,2-butanediol (4). For the final step in the synthesis, treatment with ethyl chloroformate followed by addition of aqueous ammonia gave the carbamate, and hence hydroxyphenamate (5).

References

Illustrations

Worked examples

Example 1 — a first encounter with Hydroxyphenamate

Start with the simplest possible case. Write down what Hydroxyphenamate claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Hydroxyphenamate before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Hydroxyphenamate ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Hydroxyphenamate

In research: Hydroxyphenamate appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Hydroxyphenamate in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Hydroxyphenamate is common in secondary-school and first-year university syllabi. It links to neighbouring topics Anxiolytics, Carbamates, GABAA receptor positive allosteric modulators, so understanding it makes those chapters shorter.
In everyday life: Look for Hydroxyphenamate outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Hydroxyphenamate in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Hydroxyphenamate means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Hydroxyphenamate out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Hydroxyphenamate in simple terms?

Why does Hydroxyphenamate matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Hydroxyphenamate?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Hydroxyphenamate.