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Hynda Kleinman

Hynda Kleinman is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Hynda Kleinman rather than just read about it. In short: Hynda K. Kleinman is an American cell biologist who was the chief of the cell biology section at the National Institute of Dental and Craniofacial Research from 1985 to 2006.

Hynda Kleinman — main illustration
Hynda Kleinman — illustration

Key takeaways

  • Hynda Kleinman belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Hynda Kleinman to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Hynda Kleinman from memory before moving on to harder problems.

Reference excerpt

Hynda K. Kleinman is an American cell biologist who was the chief of the cell biology section at the National Institute of Dental and Craniofacial Research from 1985 to 2006. She co-invented Matrigel.

Early life Kleinman was born into a family that valued nature, often gardening, fishing, and hiking. Kleinman's father was a trained geologist and would collect rocks and arrowheads on hikes, which sparked Kleinman's interest in chemical and biological sciences.

Life Kleinman received a B.S. in chemistry from Simmons College in 1969 and a M.S. and Ph.D. from the Massachusetts Institute of Technology in 1973. She did postdoctoral training at Tufts University. Kleinman worked at National Institutes of Health (NIH) from 1975 to 2006 in the National Institute of Dental and Craniofacial Research (NIDCR) and served as Chief of the Cell Biology Section in NIDCR's Laboratory of Cell and Developmental Biology (1985–2006). Her laboratory was the first to report the wound-healing effects of thymosin beta 4 (TB4), a synthetic version of a naturally occurring molecule. Her research accomplishments also include defining various angiogenic and antiangiogenic molecules and identifying sites on laminin for adhesion, migration, neurite outgrowth, angiogenesis, metastases and inhibition of metastases, and the respective receptors. Kleinman is a co-inventor of Matrigel. In 1992, during his first week as deputy director for intramural research, Lance Liotta appointed Kleinman to chair the new intramural women scientists' task force to investigate impediments to the advancement of women at NIH. She has received numerous awards for her research and for her efforts on behalf of women scientists. She has obtained multiple patents, many of which have been commercialized and one of which is in pivotal clinical trials. In 2006, she left the NIH to join the George Washington University as an adjunct professor in the department of biochemistry and molecular biology. She has subsequently consulted for various pharmaceutical companies Kleinman is Jewish. She was married to health statistician Joel C. Kleinman in 1968-1991 when he died. They had two daughters. She is married to computer engineer Nolan K. Danchik 1995-present.

References

Illustrations

Hynda Kleinman illustration

Worked examples

Example 1 — a first encounter with Hynda Kleinman

Start with the simplest possible case. Write down what Hynda Kleinman claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Hynda Kleinman before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Hynda Kleinman ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Hynda Kleinman

In research
Hynda Kleinman appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Hynda Kleinman in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Hynda Kleinman is common in secondary-school and first-year university syllabi. It links to neighbouring topics 20th-century American Jews, 20th-century American biologists, 20th-century American inventors, so understanding it makes those chapters shorter.
In everyday life
Look for Hynda Kleinman outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Hynda Kleinman in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Hynda Kleinman means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Hynda Kleinman out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Hynda Kleinman in simple terms?

Hynda K. Kleinman is an American cell biologist who was the chief of the cell biology section at the National Institute of Dental and Craniofacial Research from 1985 to 2006.

Why does Hynda Kleinman matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Hynda Kleinman?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Hynda Kleinman.

Tags

  • 20th-century American Jews
  • 20th-century American biologists
  • 20th-century American inventors
  • 20th-century American women biologists
  • 21st-century American Jews
  • 21st-century American biologists
  • 21st-century American inventors
  • 21st-century American women biologists
  • American cell biologists
  • American women inventors
  • George Washington University faculty
  • Jewish American scientists

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