Hypervariable may refer to:
Hypervariable sequence, a segment of a chromosome characterised by considerable variation in the number of tandem repeats at one or more loci Hypervariable locus, a locus with many alleles; especially those whose variation is due to variable numbers of tandem repeats Hypervariable region (HVR), a chromosomal segment characterized by multiple alleles within a population for a single genetic locus