In enzymology, a hyponitrite reductase is an enzyme that catalyzes the oxidation of hydroxylamine H2NOH by the nicotinamide adenine dinucleotide cation (NAD+) into hyponitrous acid HON=NOH:
2 H2NOH + 2 NAD+ ⇌ {\displaystyle \rightleftharpoons } HON=NOH + 2 NADH + 2 H+ This systematic name of this enzyme class hydroxylamine:NAD+ oxidoreductase. It is also called NADH2:hyponitrite oxidoreductase. This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. It employs one cofactor, metal.
References
Medina A, Nicholas DJ (March 1957). "Hyponitrite reductase in Neurospora". Nature. 179 (4558): 533–4. Bibcode:1957Natur.179..533M. doi:10.1038/179533a0.
