Hypoxia preconditioned plasma or hypoxia pre-conditioned plasma (abbreviated as HPP) is the (cell-free) plasma obtained after extracorporeal conditioning (i.e. culturing) of anticoagulated blood under physiological temperature (37 °C) and physiological hypoxia (1–5 %O2). Blood conditioning is typically carried out over 2 to 4 days. No high quality evidence supports its use for any medical purpose as of 2016.
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