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biology

ID3 (gene)

ID3 (gene) is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand ID3 (gene) rather than just read about it. In short: DNA-binding protein inhibitor ID-3 is a protein that in humans is encoded by the ID3 gene. Function Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM] Interactions ID3 (gene) has been shown to interact with TCF3.

ID3 (gene) — main illustration
ID3 (gene) — illustration

Key takeaways

  • ID3 (gene) belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect ID3 (gene) to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of ID3 (gene) from memory before moving on to harder problems.

Reference excerpt

DNA-binding protein inhibitor ID-3 is a protein that in humans is encoded by the ID3 gene.

Function Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM]

Interactions ID3 (gene) has been shown to interact with TCF3.

Repressors of ID3 BTG2 binds to the promoter of Id3 and represses its activity. By this mechanism, the upregulation of Id3 in the hippocampus caused by BTG2 ablation prevents terminal differentiation of hippocampal neurons.

See also Inhibitor of DNA-binding protein

References

Further reading

External links ID3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Illustrations

ID3 (gene) illustration
ID3 (gene) illustration
ID3 (gene) illustration
ID3 (gene) illustration
ID3 (gene) illustration

Worked examples

Example 1 — a first encounter with ID3 (gene)

Start with the simplest possible case. Write down what ID3 (gene) claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to ID3 (gene) before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about ID3 (gene) ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of ID3 (gene)

In research
ID3 (gene) appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses ID3 (gene) in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
ID3 (gene) is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genes on human chromosome 1, Human chromosome 1 gene stubs, Transcription factors, so understanding it makes those chapters shorter.
In everyday life
Look for ID3 (gene) outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study ID3 (gene) in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what ID3 (gene) means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain ID3 (gene) out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is ID3 (gene) in simple terms?

DNA-binding protein inhibitor ID-3 is a protein that in humans is encoded by the ID3 gene. Function Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[s…

Why does ID3 (gene) matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study ID3 (gene)?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on ID3 (gene).

Tags

  • Genes on human chromosome 1
  • Human chromosome 1 gene stubs
  • Transcription factors

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