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Wikipedia

Immunoconjugate

Immunoconjugates are antibodies conjugated (joined) to a second molecule, usually a toxin, radioisotope or label. These conjugates are used in immunotherapy and to develop monoclonal antibody therapy as a targeted form of chemotherapy when they are often known as antibody-drug conjugates. Immunoconjugates that include a radioisotope are used in radioimmunotherapy. When immunoconjugates include a toxin, they are known as immunotoxins.

References

Further reading Technology Insight: cytotoxic drug immunoconjugates for cancer therapy. 2007 looks useful from the abstract. Targeted Therapy of Cancer: New Prospects for Antibodies and Immunoconjugates. 2006 full article, 18 pages. Arming antibodies: prospects and challenges for immunoconjugates. 2005 10 pages.

Tags

  • Antineoplastic drugs
  • Immunology
  • Immunology stubs