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Indoxacarb

Indoxacarb is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Indoxacarb rather than just read about it. In short: Indoxacarb is an oxadiazine pesticide developed by DuPont that acts against lepidopteran larvae. It is marketed under the names Indoxacarb Technical Insecticide, Steward Insecticide and Avaunt Insecticide.

Indoxacarb — main illustration
Indoxacarb — illustration

Key takeaways

  • Indoxacarb belongs to science; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Indoxacarb to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Indoxacarb from memory before moving on to harder problems.

Reference excerpt

Indoxacarb is an oxadiazine pesticide developed by DuPont that acts against lepidopteran larvae. It is marketed under the names Indoxacarb Technical Insecticide, Steward Insecticide and Avaunt Insecticide. It is also used as the active ingredient in the Syngenta line of commercial pesticides: Advion and Arilon. Indoxacarb is a prodrug whose metabolite blocks of neuronal sodium channels belonging to IRAC group 22A. It is fairly lipophilic with a Kow of 4.65. This pesticide should be used with caution since some insects such as the oriental tobacco budworm (Helicoverpa assulta) become resistant when exposed. In 2021, the European Union chose not to renew Indoxacarb for use as a plant-protection insecticide. The United Kingdom still allowed its use until 2025.

Development Indoxacarb was developed by the McCann et al. team at E. I. du Pont de Nemours.

Household products Indoxacarb is the active ingredient in a number of household insecticides, including cockroach and ant baits, and can remain active after digestion. In 2012 DuPont's Professional Products including the line of Advion and Arilon products was purchased by Syngenta. Indoxacarb is the active ingredient in the pet product, Activyl, from Merck Animal Health. It is marketed to kill fleas on dogs and cats.

Toxicity to humans While toxicity to humans has not been formally studied, there is a reported case of a person consuming indoxacarb in a suicide attempt. The patient developed methemoglobinemia following ingestion. Methemoglobinemia (also known as blue baby syndrome) is a condition which ultimately decreases the effectiveness of red blood cells to exchange oxygen with organs. Methemoglobinemia can be fatal if left untreated, however when the cause is exposure to a chemical agent (not genetic) a variety of treatments are available and effective.

References

Further reading Lapied, Bruno; Françoise Grolleau; David B Sattelle (January 2001). "Indoxacarb, an oxadiazine insecticide, blocks insect neuronal sodium channels". Br J Pharmacol. 132 (2): 587–595. doi:10.1038/sj.bjp.0703853. PMC 1572588. PMID 11159709. Khambay, Bhupinder P.S. (2002). "Pyrethroid Insecticides". Pesticide Outlook. 13 (2): 49–54. doi:10.1039/b202996k. Moncada, Adriana. Environmental Fate of Indoxacarb. Environmental Monitoring Branch, Department of Pesticide Regulation, State of California. March 6, 2003 Tillman, P Glynn; Hammes, Glenn G; Sacher, Matthew; Connair, Michael; Brady, E Angela; Wing, Keith D (January 2002). "Toxicity of a formulation of the insecticide indoxacarb to the tarnished plant bug, Lygus lineolaris (Hemiptera: Miridae), and the big-eyed bug, Geocoris punctipes (Hemiptera: Lygaeidae)". Pest Manag. Sci. 58 (1): 92–100. doi:10.1002/ps.426. PMID 11838290. Archived from the original on 2008-08-07.

External links DuPont Steward insecticide - FAQs. Updated 20 January 2007. Archived 21 August 2008 at the Wayback Machine Retrieved 2012-11-11 Indoxacarb in the Pesticide Properties DataBase (PPDB)

Illustrations

Indoxacarb: Stereo wireframe model of (4aS)-Indoxacarb
Stereo wireframe model of (4aS)-Indoxacarb

Worked examples

Example 1 — a first encounter with Indoxacarb

Start with the simplest possible case. Write down what Indoxacarb claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Indoxacarb before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Indoxacarb ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Indoxacarb

In research
Indoxacarb appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Indoxacarb in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Indoxacarb is common in secondary-school and first-year university syllabi. It links to neighbouring topics Carbamates, Carboxylate esters, Methyl esters, so understanding it makes those chapters shorter.
In everyday life
Look for Indoxacarb outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Indoxacarb in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Indoxacarb means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Indoxacarb out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Indoxacarb in simple terms?

Indoxacarb is an oxadiazine pesticide developed by DuPont that acts against lepidopteran larvae. It is marketed under the names Indoxacarb Technical Insecticide, Steward Insecticide and Avaunt Insecticide.

Why does Indoxacarb matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Indoxacarb?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Indoxacarb.

Tags

  • Carbamates
  • Carboxylate esters
  • Methyl esters
  • Nitrogen heterocycles
  • Oxygen heterocycles
  • Pesticides
  • Sodium channel blockers
  • Trifluoromethyl ethers
  • Ureas

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