engineering

Iron-chelate-transporting ATPase

Iron-chelate-transporting ATPase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Iron-chelate-transporting ATPase rather than just read about it. In short: In enzymology, an iron-chelate-transporting ATPase (EC 3.6.3.34) is an enzyme that catalyzes the chemical reaction ATP + H2O + iron chelateout ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate + iron chelatein The 3 substrates of this enzyme are ATP, H2O, and iron chelate, whereas its 3 products are ADP, phosphate, and iron chelate. This enzyme belongs to the family of hydrolases, specifically those acting on ac…

Key takeaways

Iron-chelate-transporting ATPase belongs to engineering; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Iron-chelate-transporting ATPase to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Iron-chelate-transporting ATPase from memory before moving on to harder problems.

Reference excerpt

In enzymology, an iron-chelate-transporting ATPase (EC 3.6.3.34) is an enzyme that catalyzes the chemical reaction

ATP + H2O + iron chelateout ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate + iron chelatein The 3 substrates of this enzyme are ATP, H2O, and iron chelate, whereas its 3 products are ADP, phosphate, and iron chelate. This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (iron-chelate-importing). This enzyme participates in abc transporters - general.

Structural studies As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB: 1L2P, PDB: 1L6T, and PDB: 2IHY.

References

Shea CM, McIntosh MA (1991). "Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli". Mol. Microbiol. 5 (6): 1415–28. doi:10.1111/j.1365-2958.1991.tb00788.x. PMID 1838574. S2CID 25193069. Koster W, Bohm B (1992). "Point mutations in two conserved glycine residues within the integral membrane protein FhuB affect iron(III) hydroxamate transport". Mol. Gen. Genet. 232 (3): 399–407. doi:10.1007/bf00266243. PMID 1588908. S2CID 28286920. Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. doi:10.1016/0923-2508(96)81050-3. PMID 7569321. Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. Advances in Microbial Physiology. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 9780120277407. PMID 9889977.{{cite journal}}: CS1 maint: periodical has ISBN (link) Mademidis A, Koster W (1998). "Transport activity of FhuA, FhuC, FhuD, and FhuB derivatives in a system free of polar effects, and stoichiometry of components involved in ferrichrome uptake". Mol. Gen. Genet. 258 (1–2): 156–65. doi:10.1007/s004380050718. PMID 9613584. S2CID 25378659.

Worked examples

Example 1 — a first encounter with Iron-chelate-transporting ATPase

Start with the simplest possible case. Write down what Iron-chelate-transporting ATPase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Iron-chelate-transporting ATPase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Iron-chelate-transporting ATPase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Iron-chelate-transporting ATPase

In research: Iron-chelate-transporting ATPase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Iron-chelate-transporting ATPase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Iron-chelate-transporting ATPase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 3.6.3, EC 3.6 stubs, Enzymes of known structure, so understanding it makes those chapters shorter.
In everyday life: Look for Iron-chelate-transporting ATPase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

Ask Teacher Smith questions about this articleOpens your AI tutor with a question about “Iron-chelate-transporting ATPase” →

Affiliate

Preply — study more efficiently by working with a personal tutor. 50% off.

How to study Iron-chelate-transporting ATPase in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Iron-chelate-transporting ATPase means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Iron-chelate-transporting ATPase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Iron-chelate-transporting ATPase in simple terms?

In enzymology, an iron-chelate-transporting ATPase (EC 3.6.3.34) is an enzyme that catalyzes the chemical reaction ATP + H2O + iron chelateout ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate + iron chelatein The 3 substrates of this enzyme are ATP, H2O, and iron chelate, whereas its 3 product…

Why does Iron-chelate-transporting ATPase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Iron-chelate-transporting ATPase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Iron-chelate-transporting ATPase.