Isostrychnine is a monoterpenoid indole alkaloid and a structural isomer of strychnine. It is a secondary plant metabolite and may have antitumor activity.
Occurrence Isostrychnine has been isolated from plant extracts of Strychnos species (e.g the seeds of Strychnos nux-vomica (strychnine tree) or the roots of Strychnos icaja). It is also present in Strychnos ignatii.
Pharmacology One study observed inhibitory effects against Hep G2 cell proliferation. Another study found isostrychnine arrested the growth of the human hepatocarcinoma cell line SMMC 7721.
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