biology

Ivan R. Nabi

Ivan R. Nabi is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Ivan R. Nabi rather than just read about it. In short: Ivan Robert Nabi is a Canadian cell biologist and academic. He serves as professor and director of Imaging at the Life Sciences Institute of the University of British Columbia in Vancouver, Canada.

Key takeaways

Ivan R. Nabi belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Ivan R. Nabi to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Ivan R. Nabi from memory before moving on to harder problems.

Reference excerpt

Ivan Robert Nabi is a Canadian cell biologist and academic. He serves as professor and director of Imaging at the Life Sciences Institute of the University of British Columbia in Vancouver, Canada. His research focuses on cellular domains and their roles in cancer progression and metastasis.

Education Nabi earned his Bachelor of Science degree in Biochemistry from McGill University, Montreal, Quebec, in 1983. He completed his Ph.D. in Cancer Metastasis at the Weizmann Institute of Science in 1989.

Career Nabi pursued postdoctoral fellowships at the Michigan Cancer Foundation and Cornell University Medical College. His academic career includes positions at the Université de Montréal, where he served as Assistant, Associate and then Full Professor in the Departments of Pathology and Cell Biology and Anatomy from 1992 to 2005. In 2004, he joined the University of British Columbia as a professor in the Department of Cellular and Physiological Sciences at the Life Sciences Institute.

Research contributions Nabi's research spans a range of topics in cell biology with application to cancer metastasis and viral infections such as Zika and SARS-CoV-2. His early work identified the Gp78 receptor of Autocrine motility factor during his graduate studies, later identified as an endoplasmic reticulum-associated E3 ubiquitin ligase. His recent work has identified a role for Gp78 in regulation of basal mitophagy, production of reactive oxygen species and a distinct class of ribosome-studded mitochondria-endoplasmic reticulum contacts (riboMERCs). He has studied cellular domains including Lipid raft, caveolae, non-caveolar caveolin-1 scaffolds, and the galectin lattice, elucidating their regulation of cancer cell signaling and migration. His recent focus involves applying weakly supervised computational machine learning approaches to super-resolution microscopy for biological discovery, applying network analysis to single molecule microscopy to identify non-caveolar scaffolds and developing sub-pixel super-resolution approaches to detect mitochondria-endoplasmic reticulum contact sites.

Awards and service Nabi is currently the Associate Editor for Biochemistry Society Transactions. He received the CPS Researcher of the Year Award from the University of British Columbia in 2008 and the Ambassador Award from the Cancer Research Society in 2017. He has also served in leadership roles such as Chair of the Scientific Advisory Board for the Cancer Research Society and Founding Member of the School of Biomedical Engineering at the University of British Columbia.

Selected publications Alan, Parsa; Vandevoorde, Kurt R.; Joshi, Bharat; Cardoen, Ben; Gao, Guang; Mohammadzadeh, Yahya; Hamarneh, Ghassan; Nabi, Ivan R. (November 2022). "Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS". Cellular and Molecular Life Sciences. 79 (11): 565. doi:10.1007/s00018-022-04585-8. PMC 9596570. PMID 36284011. Cardoen, Ben; Vandevoorde, Kurt R.; Gao, Guang; Ortiz-Silva, Milene; Alan, Parsa; Liu, William; Tiliakou, Ellie; Vogl, A. Wayne; Hamarneh, Ghassan; Nabi, Ivan R. (1 January 2024). "Membrane contact site detection (MCS-DETECT) reveals dual control of rough mitochondria–ER contacts". Journal of Cell Biology. 223 (1) e202206109. doi:10.1083/jcb.202206109. PMC 10638097. PMID 37948126. Khater, Ismail M.; Liu, Qian; Chou, Keng C.; Hamarneh, Ghassan; Nabi, Ivan Robert (8 July 2019). "Super-resolution modularity analysis shows polyhedral caveolin-1 oligomers combine to form scaffolds and caveolae". Scientific Reports. 9 (1): 9888. Bibcode:2019NatSR...9.9888K. doi:10.1038/s41598-019-46174-z. PMC 6614455. PMID 31285524.{{cite journal}}: CS1 maint: unflagged free DOI (link)

References

Worked examples

Example 1 — a first encounter with Ivan R. Nabi

Start with the simplest possible case. Write down what Ivan R. Nabi claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Ivan R. Nabi before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Ivan R. Nabi ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Ivan R. Nabi

In research: Ivan R. Nabi appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Ivan R. Nabi in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Ivan R. Nabi is common in secondary-school and first-year university syllabi. It links to neighbouring topics 21st-century Canadian biologists, 21st-century Canadian scientists, Academic staff of the University of British Columbia, so understanding it makes those chapters shorter.
In everyday life: Look for Ivan R. Nabi outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Ivan R. Nabi in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Ivan R. Nabi means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Ivan R. Nabi out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Ivan R. Nabi in simple terms?

Ivan Robert Nabi is a Canadian cell biologist and academic. He serves as professor and director of Imaging at the Life Sciences Institute of the University of British Columbia in Vancouver, Canada.

Why does Ivan R. Nabi matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Ivan R. Nabi?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Ivan R. Nabi.