biology

Ivan Đikić

Ivan Đikić is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Ivan Đikić rather than just read about it. In short: Ivan Đikić (born 28 May 1966) is a Croatian-German molecular biologist who is the Director of the Institute of Biochemistry II at Goethe University Frankfurt. Scientific career In 1991, he earned his MD degree from the Faculty of Medicine at the University of Zagreb.

Key takeaways

Ivan Đikić belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Ivan Đikić to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Ivan Đikić from memory before moving on to harder problems.

Reference excerpt

Ivan Đikić (born 28 May 1966) is a Croatian-German molecular biologist who is the Director of the Institute of Biochemistry II at Goethe University Frankfurt.

Scientific career In 1991, he earned his MD degree from the Faculty of Medicine at the University of Zagreb. After finishing his medical studies, he continued to pursue his PhD thesis in molecular biology at the University of Zagreb and at the New York University School of Medicine until 1997. He continued to work as a postdoctoral fellow in the laboratory of Joseph Schlessinger in New York from 1995 to 1997 before starting his own group at the Ludwig Institute for Cancer Research in Uppsala (Sweden). In 2002, Đikić was appointed as a Professor at Goethe University Frankfurt. He followed in Werner Müller-Esterl's footsteps as Director of the Institute of Biochemistry II in 2009. In addition, Đikić was the first Scientific Director (2009–2013) of the Buchmann Institute for Molecular Life Sciences, a cross-faculty, interdisciplinary institute at Goethe University which was founded as part of the Cluster of Excellence Macromolecular Complexes. He is speaker of the Collaborative Research Center 1177 on selective autophagy, and speaker of the LOEWE program "Ubiquitin Networks". Đikić has an affiliation as Professor with the School of Medicine University of Split, where he established an outstation lab in Split University and transferring technologies to Croatia. In addition, Đikić has been recognized by one of the highest civilian honours, The Order of Duke Branimir, bestowed by the President of Croatia. Đikić is member of several academic societies, including the number of organizations including the European Molecular Biology Organization (since 2004), the World Academy of Art and Science (since 2008), German National Academy of Sciences Leopoldina (since 2010), the American Academy of Arts and Sciences (since 2019), the Croatian Academy of Medical Science, and the European Academy of Sciences. He is a member of the editorial board for Cell.

Research Đikić's research focuses on deciphering molecular mechanisms of cellular signaling pathways, which have a high relevance to human diseases such as cancer, neurodegenerative disorders and inflammation. Early on, he started to focus on ubiquitin to understand how this modification controls multiple cellular functions, and managed to prove a concept of ubiquitin signal recognition by specialized domains serving as specific receptors. More recently, his team has revealed the functions of linear ubiquitin chains in pathogen defense and overall immune response. He expanded his research to the field of selective autophagy, recognizing the enormous impact of the LC3/GABARAP signaling network displaying striking mechanistic similarities to ubiquitin. One major focus is on the crosstalk between autophagy and endocytic machineries, and in this context he has gained fundamental insight in autophagic processes at the endoplasmic reticulum (ER-phagy).

Education In 1998, Đikić initiated the series of Dubrovnik Cell Signalling Conferences, which has been sponsored by EMBO continuously since 2004. Moreover, he is actively involved in organization of EMBO Meetings (Ubiquitin Meetings in 2015, 2013; Autophagy Meeting 2011, Cellular Microbiology/Cell Biology Meeting in 2010, 2008), EMBO Courses (2012, 2010, 2008, 2006 on Ubiquitin/SUMO; 2010 on Ubiquitin & DNA damage) as well as Keystone and CSH Meetings. In July 2016, he was hosting the Frankfurt Conference on Ubiquitin and Autophagy together with Volker Dötsch, Hubert Serve and Heide Genau.

Personal life He's married to Inga Đikić with whom he has three children. He's a Christian of Roman Catholic denomination and has stated publicly that he sees no conflict between science and religion.

Honors and awards 1997–2003 Research Award, Boehringer Ingelheim Fonds Germany 2000–2004 Award of the Strategic Funds for Young Leaders, Sweden 2002 Lilla Fernström Award, Lund, Sweden 2006 AACR Award for Outstanding Achievement in Cancer Research, Washington, US 2006 Young Cancer Researcher Award, European Association for Cancer Research, Budapest, Hungary 2006 Binder Innovation Prize, German Society for Cell Biology, Braunschweig, Germany 2006 Biomedical Science Prize 2006, Glaxo-Smith-Kline-Foundation, Munich, Germany 2008 Award of the International Society of Blood Purification, Brijuni Islands 2008 City of Split Award – Annual Prize for Science, Croatia 2009 Sir Hans Krebs Prize, Medical Faculty Hannover, Hannover, Germany 2010 German Cancer Prize, DKG Berlin, Germany 2010–2015 European Research Council (ERC) Advanced Grant, Brüssel, Belgium 2010 Order of Duke Branimir for international promotion of Croatia 2013 Ernst Jung Prize for Medicine 2013, Jung Foundation for Science and Research, Hamburg, Germany 2013 Gottfried Wilhelm Leibniz Prize of the German Research Foundation, Bonn, Germany 2013 William C. Rose Award 2013, American Association for Molecular Biology and Biochemistry for outstanding achievements, Boston, US 2014/2015 Vallee Visiting Professorship, Harvard Medical School, Boston, US 2015 Member of the Academia Europaea 2019 American Academy of Arts & Sciences 2023 Louis-Jeantet Prize for Medicine

References

External links Bibliography at the United States National Library of Medicine

Illustrations

Worked examples

Example 1 — a first encounter with Ivan Đikić

Start with the simplest possible case. Write down what Ivan Đikić claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Ivan Đikić before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Ivan Đikić ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Ivan Đikić

In research: Ivan Đikić appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Ivan Đikić in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Ivan Đikić is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1966 births, 21st-century Croatian scientists, American medical researchers, so understanding it makes those chapters shorter.
In everyday life: Look for Ivan Đikić outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Ivan Đikić in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Ivan Đikić means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
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Frequently asked questions

What is Ivan Đikić in simple terms?

Ivan Đikić (born 28 May 1966) is a Croatian-German molecular biologist who is the Director of the Institute of Biochemistry II at Goethe University Frankfurt. Scientific career In 1991, he earned his MD degree from the Faculty of Medicine at the University of Zagreb.

Why does Ivan Đikić matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Ivan Đikić?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Ivan Đikić.