Isobel Katherine "Izzie" Stevens, M.D. is a fictional character from the medical drama television series Grey's Anatomy, which airs on the American Broadcasting Company (ABC) in the United States. The character was created by series producer Shonda Rhimes, and was portrayed by actress Katherine Heigl from 2005 to 2010. Introduced as a surgical intern at the fictional Seattle Grace Hospital, Izzie worked her way up to resident level, while her relationships with her colleagues Meredith Grey (Ellen Pompeo), Cristina Yang (Sandra Oh), Alex Karev (Justin Chambers) and George O'Malley (T. R. Knight) formed a focal point of the series. Heigl garnered widespread critical acclaim for her performance as Izzie and received numerous awards and nominations for her role, winning Outstanding Supporting Actress in a Drama Series at the 59th Primetime Emmy Awards in 2007. Her win was particularly notable in the history of Grey's Anatomy, as Heigl remains the only cast member to have won an individual Primetime Emmy Award for acting for her performance in the series. Although the series itself has received and won multiple Emmy Awards across various categories, none of its other principal cast members have won an individual acting Emmy. She was critical of the character's development during the show's fourth season, particularly her romance with her on-screen best friend George. She declined to pursue a nomination for the 2008 Emmy Awards, citing insufficient material in the role. After speculation that Izzie would be killed off in the fifth season, the character was diagnosed with Stage 4 metastatic melanoma. She married Alex in the series' 100th episode, and afterwards, her tumor was successfully removed. Heigl made her final series regular appearance as Izzie in the sixth season, leaving Seattle after Alex refused to resume their marriage. The actress requested to be released from her contract 18 months early, in order to spend more time with her family. Ten years after her final appearance, the character's fate was revealed in a season 16 episode, where she makes a visual cameo re-appearance.
Storylines
Background Isobel Katherine "Izzie" Stevens (born 6/23/1981) is the daughter of a single mother named Robbie (Sharon Lawrence). They lived together in a trailer park, and Stevens was affectionately nicknamed "Cricket" by her mother. A teenage pregnant patient of hers named Cheyenne (Regine Nehy) identifies her trailer as being situated behind a church. Her maternal grandmother died of thyroid cancer sometime before her surgical residency. Growing up, Izzie was encouraged to go into the medical field by her high school biology teacher, Dr. Singer (Joel Grey). When Izzie was 15, she became pregnant with her first biological child, Hannah Klein (Liv Hutchings) and this caused her to have friction with cheerleaders at her high school. In his Alzheimer's state, Dr. Singer recognizes the father of her child as a fellow high school student. She placed the child for adoption at age 16 after giving birth in 1996. Izzie privately named her daughter Sarah despite her adoptive parents naming her Hannah. Two years later, Stevens departed her hometown of Chehalis, Washington at age 18 and never returned until her third year of residency. After snooping through her file, Lexie Grey (Chyler Leigh) also discovers Stevens attended night school for college and consequently took six years to finish her undergraduate degree.
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![Izzie Stevens: Heigl said she felt "attached to [Chambers]", and their characters "being together" which she felt was "supposed to be, but you can't have it all" in an October 2010 interview.[62]](https://upload.wikimedia.org/wikipedia/commons/thumb/b/be/Justin_Cambers_2014_%28cropped%29.jpg/1280px-Justin_Cambers_2014_%28cropped%29.jpg?utm_source=en.wikipedia.org&utm_campaign=parser&utm_content=thumbnail)
![Izzie Stevens: Heigl was critical of Izzie's relationship with George (T. R. Knight), deeming it "a ratings-ploy".[82]](https://upload.wikimedia.org/wikipedia/commons/thumb/d/d2/TR_Knight_cropped.jpg/330px-TR_Knight_cropped.jpg?utm_source=en.wikipedia.org&utm_campaign=parser&utm_content=thumbnail)
