biology

Jan O. Korbel

Jan O. Korbel is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Jan O. Korbel rather than just read about it. In short: Jan O. Korbel (born 1975) is a German scientist working in the fields of human genetics, genomics and computational biology.

Key takeaways

Jan O. Korbel belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Jan O. Korbel to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Jan O. Korbel from memory before moving on to harder problems.

Reference excerpt

Jan O. Korbel (born 1975) is a German scientist working in the fields of human genetics, genomics and computational biology. He is the Interim Head of Site of the European Molecular Biology Laboratory (EMBL) site in Heidelberg, Germany.

Education After receiving his PhD in 2005 from Humboldt University of Berlin, he pursued his postdoctoral research at Yale University, New Haven, Connecticut (USA) with Mark B. Gerstein.

Research and career He is a tenured principal investigator, and also Heading the Data Science Centre at the EMBL. He is also a senior scientist in the Genome Biology Unit at the EMBL, is leading a bridging research division at the German Cancer Research Center (DKFZ), and is an honorary professor ("Honorarprofessor") at Heidelberg University. A particular focus of the Korbel group is on investigating a particular form of mutation, genomic structural variation, which includes deletions, inversions and more complex chromosomal rearrangements such as chromothripsis events that can occur in healthy individuals and in context of disease. His group's principal research objective is to understand genomic structural variations as a basis of phenotypic variation and cancer development. In addition to his research activities, Jan Korbel is promoting interdisciplinary dialogues in bioethics, and the application of genome sequencing in Genomic Medicine.

Awards and recognition He received several academic prizes, including:

the Chica and Heinz Schaller Research Award (2014), the Manfred-Fuchs-Prize for his bioethical research (2015), the 2018 HMLS Investigator Award, and the Pezcoller Foundation–EACR Cancer Researcher Award (2018). He is an elected member of Germany's National Academy of Sciences Leopoldina (2015) and of the European Molecular Biology Organization (EMBO) (2016). He is also a fellow of the European Academy of Cancer Sciences. Jan Korbel is also a European Research Council (ERC) investigator.

References

External links https://www.embl.de/research/units/genome_biology/korbel/index.html

Worked examples

Example 1 — a first encounter with Jan O. Korbel

Start with the simplest possible case. Write down what Jan O. Korbel claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Jan O. Korbel before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Jan O. Korbel ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Jan O. Korbel

In research: Jan O. Korbel appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Jan O. Korbel in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Jan O. Korbel is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1975 births, German bioinformaticians, German geneticists, so understanding it makes those chapters shorter.
In everyday life: Look for Jan O. Korbel outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Jan O. Korbel in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Jan O. Korbel means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Jan O. Korbel out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Jan O. Korbel in simple terms?

Jan O. Korbel (born 1975) is a German scientist working in the fields of human genetics, genomics and computational biology.

Why does Jan O. Korbel matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Jan O. Korbel?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Jan O. Korbel.