astronomy

Judith Clements

Judith Clements is a astronomy topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Judith Clements rather than just read about it. In short: Judith Ann Clements is an Australian academic and educator, specializing in Kallikrein proteases in prostate and ovarian cancers. Clements is the scientific director at the Australian Prostate Cancer Research Centre – Queensland and was head of the Cancer Research Program at the Institute of Health and Biomedical Innovation (IHBI) of Queensland University of Technology at the Translational Research Institute (Austra…

Key takeaways

Judith Clements belongs to astronomy; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Judith Clements to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Judith Clements from memory before moving on to harder problems.

Reference excerpt

Judith Ann Clements is an Australian academic and educator, specializing in Kallikrein proteases in prostate and ovarian cancers. Clements is the scientific director at the Australian Prostate Cancer Research Centre – Queensland and was head of the Cancer Research Program at the Institute of Health and Biomedical Innovation (IHBI) of Queensland University of Technology at the Translational Research Institute (Australia) from 1997 to 2014. Her biography was published in the Cancer and Metastasis Reviews in 2019

Research The Cancer Research Program led by Clements at QUT-IHBI, aims to more clearly understand the molecular and cellular basis for the development, progression, and metastasis of solid tumours. Clements has commented on her research, stating:

"The primary interest of my group within the Hormone Dependent Cancer Program is the tissue kallikrein family of serine proteases. Our group was one of three worldwide that identified and characterised the expanded human tissue kallikrein gene locus on chromosome 19q13.4 in 1999. Since that time, our research has focused on defining the roles of particular kallikreins, and their variant forms, in hormone dependent cancers such as prostate, ovarian and endometrial cancer. We have used conventional/real time PCR and immunohistochemistry to determine the association of kallikrein expression with clinical disease to determine their usefulness as biomarkers for detection, prognostic outcome and therapeutic approaches. We are also utilizing over-expression and knockout systems to determine the effect of kallikrein expression in cancer cell lines at the cell biology level. Other studies in progress are directed to understanding the structure/function of the kallikreins, their substrate specificity and in vivo interacting proteins and genomic regulation. Other protease research interests are the type 2 trans membrane serine proteases (with Dr John Hooper) and the ADAMs (with Prof Adrian Herington and Dr Dimitri Odorico).

Education Clements completed her PhD in Endocrinology at Monash University in 1989, her Master of Applied Science in 1983, after completing her Bachelor of Applied Science in 1982 and Diploma of Laboratory Technology in 1969 at the Royal Melbourne Institute of Technology.

Awards 2019 QLD Greats Premier Medal 2017 Fellow of the Australian Academy of Health and Medical Sciences 2015 Companion of the Order of Australia 2012 Women in Technology (WiT) Biotech Outstanding Achievement Award 2011 Queensland University of Technology Vice Chancellor's Award for Research Excellence 2007 Gold Medal, E.K.Frey–E.Werle Foundation for pioneering work in the Kallikrein field 2006 Research featured in "Ten Of The Best" National Health and Medical Research Council funded health and medical research successes 2005 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting 2001 Queensland University of Technology Faculty of Science Distinguished Award for Excellence in Research 2000 National Health and Medical Research Council Principal Research Fellowship 2000 Silver Medal and Honorary Membership of the E.K.Frey–E.Werle Foundation (awarded at the International Conference, Kinin 2000, Munich) 1998 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting 1995 National Health and Medical Research Council Senior Research Fellowship 1991 Prize for an "Outstanding Presentation", Kinin 91, International Conference on Kallikreins and Kinins, Munich, Germany.

Publications

Zhao, Hong, Dong, Ying, Quan, Jingjing, Smith, Robert, Lam, Alfred, Weinstein, Stephen, Clements, Judith, Johnson, Newell W., and Gao, Jin (2011) Correlation of the expression of human kallikrein-related peptidases 4 and 7 with the prognosis in oral squamous cell carcinoma. Head and Neck, 33 (4). pp. 566–572. Gao, Jin, Collard, Rachael L., Bui, Loan, Herington, Adrian C., Nicol, David L., and Clements, Judith A. (2007) Kallikrein 4 is a potential mediator of cellular interactions between cancer cells and osteoblasts in metastatic prostate cancer. Prostate, 67 (4). pp. 348–360.

References

External links Prostate Cancer Research Alliance Prostate Cancer Research Centre profile

Worked examples

Example 1 — a first encounter with Judith Clements

Start with the simplest possible case. Write down what Judith Clements claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In astronomy, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Judith Clements before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Judith Clements ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Judith Clements

In research: Judith Clements appears in astronomy research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Judith Clements in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Judith Clements is common in secondary-school and first-year university syllabi. It links to neighbouring topics Australian medical researchers, Cancer researchers, Companions of the Order of Australia, so understanding it makes those chapters shorter.
In everyday life: Look for Judith Clements outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Judith Clements in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Judith Clements means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Judith Clements out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Judith Clements in simple terms?

Why does Judith Clements matter?

Because it connects several astronomy ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Judith Clements?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Judith Clements.