biology

KDM4C

KDM4C is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand KDM4C rather than just read about it. In short: Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene. Structure This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains.

Key takeaways

KDM4C belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect KDM4C to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of KDM4C from memory before moving on to harder problems.

Reference excerpt

Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene.

Structure This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein belongs to the alpha-ketoglutarate-dependent hydroxylase superfamily.

Function It functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. A expressional decrease of KDM4C was found during cardiac differentation of murine embryonic stem cells.

References

Illustrations

Worked examples

Example 1 — a first encounter with KDM4C

Start with the simplest possible case. Write down what KDM4C claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to KDM4C before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about KDM4C ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of KDM4C

In research: KDM4C appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses KDM4C in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: KDM4C is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 1.14.11, Genes mutated in mice, Genes on human chromosome 9, so understanding it makes those chapters shorter.
In everyday life: Look for KDM4C outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study KDM4C in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what KDM4C means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain KDM4C out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is KDM4C in simple terms?

Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene. Structure This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains.

Why does KDM4C matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study KDM4C?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on KDM4C.